Follow-up study on symptom distress in esophageal cancer patients undergoing repeated dilation  

作　　者：Li Liu Qian-Wen Liu Xiao-Dan Wu Shu-Yue Liu Hui-Jiao Cao Yu-Tong Hong Hui-Ying Qin 

机构地区：[1]Thoracic Department,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China [2]State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Guangzhou 510060,Guangdong Province,China [3]Department of Endoscopy,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China [4]Department of Colorectal Surgery,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China [5]Hepatopancreatobiliary Surgery Department,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China [6]Traditional Chinese Medicine Department,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China [7]Department of Nursing,Sun Yat-sen University Cancer Center,Guangzhou 510060,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2020年第16期3503-3514,共12页世界临床病例杂志

基　　金：Supported by Natural Science Foundation of Guangdong Province of China,No.2017A030313449;Science and Technology Planning Project of Guangdong Province of China,No.A2018057。

摘　　要：BACKGROUND Repeated endoscopic probe dilatation is the most preferred treatment for esophageal stenosis which may cause high levels of symptom distress in the patient’s home rehabilitation stage.AIM To explore the changes in the symptom distress level and its correlation with the dilation effect in patients with esophageal carcinoma undergoing repeated dilations for lumen stenosis.METHODS The difference(R2-R1)between the diameter of the esophageal stenosis opening(R1)of the patients before dilation(R1)and after dilation(R2)was calculated to describe the extent and expansion of the esophageal stenosis before and after dilation.The M.D.Anderson Symptom Inventory was used to describe the symptom distress level of patients with dilation intermittence during their stay at home and to explore the correlation between the dilation effect and symptom distress level.RESULTS The diameter of the esophagus(R1)increased before each dilation in patients undergoing esophageal dilation(P<0.05).The diameter(R2)increased after dilation(P<0.05);the dilation effect(R2-R1)decreased with the number of dilations(P<0.05).The total symptom distress score significantly increased with the number of dilations(P<0.05).The symptom distress scores of the patients were negatively correlated(P<0.05)with the previous dilation effect(R2-R1)and the esophageal diameter(R2)after the previous dilation.After the 1 st to 4 th dilations,the patient’s symptom distress score was negatively correlated with the esophageal diameter(R12)before the next dilation,while there was no significant correlation(P>0.05)with the other dilations.CONCLUSION In patients who have undergone repeated dilations,better effect stands for lower symptom distress level and the increase in symptom distress has a prompt effect on the severity of the next occurrence of restenosis.

关 键 词：Esophageal carcinoma Dilation of esophageal stenosis Symptom distress Dilation effect Lumen stenosis Repeated dilation 

分 类 号：R735.1[医药卫生—肿瘤]