Multifocal neuroendocrine cell hyperplasia accompanied by tumorlet formation and pulmonary sclerosing pneumocytoma:A case report  

作　　者：Xiao-Yu Han Yuan-Yuan Wang Hong-Quan Wei Guang-Zhao Yang Jian Wang Yu-Zhu Jia Wei-Qun Ao 

机构地区：[1]Department of Pathology,Tongde Hospital of Zhejiang Province,Hangzhou 310012,Zhejiang Province,China [2]Department of Radiology,Tongde Hospital of Zhejiang Province,Hangzhou 310012,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2020年第16期3583-3590,共8页世界临床病例杂志

摘　　要：BACKGROUND Pulmonary tumorlets are nodular hyperplastic neuroendocrine cells(NECs)that extend beyond the basement membrane.They often coexist with other lung diseases such as fibrosis and bronchiectasis,but rarely accompanied by pulmonary sclerosing pneumocytoma(PSP),which has not been reported in the literature.CASE SUMMARY A 54-year-old woman was admitted to the hospital because she had symptoms of bloody sputum for more than 4 mo and hemoptysis for 1 wk.Computed tomography images showed atrophy accompanied by infections in the middle lobe of her right lung.Moreover,numerous nodules were identified in the middle lobe of the right lung.The patient underwent thoracoscopic pneumonectomy of the middle lobe of the right lung,and the resected mass was pathologically confirmed to have bronchiectasis,multifocal NEC hyperplasia accompanied by tumorlet,and PSP.CONCLUSION Our report presents a rare clinical case of bronchiectasis complicated with multifocal NEC hyperplasia,tumorlet,and PSP.

关 键 词：Neuroendocrine cell hyperplasia Tumorlet formation Pulmonary sclerosing pneumocytoma Pulmonary tumor 

分 类 号：R734.2[医药卫生—肿瘤]