降尿酸天然生物活性物质作用机制研究进展  

Research progress on the mechanism of uric acid-lowering natural bioactive compounds

作　　者：蒋林宏 杨锡洪 谢静雯 解万翠 JIANG Lin-hong;YANG Xi-hong;XIE Jing-wen;XIE Wan-cui(College of Marine Science and Biological Engineering,Qingdao University of Science&Technology,Qingdao,Shandong 266042,China;Key Laboratory for Biochemical Engineering of Shandong Province,Qingdao,Shandong 266042,China;Qingdao Guantong Biotechnology Co.,Ltd.,Qingdao,Shandong 266002,China;Shanghao Science and Technology Co.,Ltd.,Qingdao,Shandong 266002,China)

机构地区：[1]青岛科技大学海洋科学与生物工程学院,山东青岛266042 [2]山东省生物化学工程重点实验室,山东青岛266042 [3]青岛贯同生物科技有限公司,山东青岛266002 [4]尚好科技有限公司,山东青岛266002

出　　处：《食品与机械》2020年第8期210-216,共7页Food and Machinery

基　　金：国家重点研发计划项目(编号:2018YFD0901105);国家自然科学基金项目(编号:31671825)。

摘　　要：文章基于嘌呤代谢及尿酸的生成途径,概述天然生物活性物质的4种降尿酸方式及作用机制,重点分析了天然提取物、蛋白酶解物及多肽、益生菌等活性物质的降尿酸作用方式及研究成果,并对药食资源开发、医学辅助食品及抗痛风天然药物的研制前景进行展望。Based on purine metabolism and the pathway of uric acid,four kinds of uric acid-lowering modes and mechanisms of natural bioactive compounds were summarized,mainly analyzed the uric acid-lowering modes and research results of natural extracts,protein enzymatic hydrolysates,polypeptides,probiotics and other active compounds.It is provided guidance for the development of medicinal resources,medical auxiliary food and natural anti-gout drugs.

关 键 词：生物活性物质 降尿酸 益生菌 肽 作用机制 

分 类 号：TQ460.1[化学工程—制药化工]