青少年低中度近视患者夜戴角膜塑形镜的临床效果  

Clinical results of orthokeratology therapy in adolescents with low to moderate myopia

作　　者：尹叶薇 赵旸 傅艳燕 向爱群 吴小影[1] 文丹[1] YIN Yewei;ZHAO Yang;FU Yanyan;XIANG Aiqun;WU Xiaoying;WEN Dan(Eye Center,Xiangya Hospital,Central South University,Changsha 410008,China)

机构地区：[1]中南大学湘雅医院眼科中心,长沙410008

出　　处：《中南大学学报（医学版）》2020年第8期966-972,共7页Journal of Central South University ：Medical Science

基　　金：湖南省自然科学基金(2015JJ4093);长沙市科技计划项目(kq1701079)。

摘　　要：目的:观察青少年低中度近视患者夜戴角膜塑形镜6个月后的临床效果。方法:回顾性分析69例青少年低中度近视患者的病例资料。根据戴镜前球镜度数分为低度近视组(34例,球镜度数为-3.00^-0.75 D)和中度近视组(35例,球镜度数为-5.75^-3.25 D)。比较两组患者戴镜前和戴镜6个月后的裸眼视力(uncorrected distance visual acuity,UDVA)、眼压、角膜内皮细胞计数、眼轴、斯特列尔比(Strehl ratio,SR)、调制传递函数(modulation transfer function,MTF)、Q值和波前像差的变化。结果:两组患者的UDVA与戴镜前相比均明显提高(均P<0.05);两组患者的眼压、角膜内皮细胞计数较戴镜前均无显著变化(均P>0.05);眼轴较戴镜前均显著增加(均P<0.05),但两组之间差异均无统计学意义(均P>0.05);两组患者的Q值较戴镜前均显著增加,且中度近视组更明显(均P<0.05);两组患者SR和MTF较戴镜前均明显增加(均P<0.05),但两组之间差异均无统计学意义(均P>0.05);两组患者的总像差、总低阶像差、离焦较戴镜前均减小(均P<0.05),中度近视组的变化较低度近视组更显著(均P<0.01);低度近视组患者的总高阶像差较戴镜前显著增加(P<0.05);两组患者的垂直散光、球差、水平彗差、垂直彗差和水平三叶草较戴镜前均显著增加(均P<0.05),且中度近视组的球差、垂直彗差和水平三叶草的变化更显著(均P<0.05)。结论:角膜塑形镜在青少年低中度近视患者中可取得良好的近视矫正效果,对中度近视的矫正效果要稍优于低度近视。Objective:To observe the clinical results of orthokeratology therapy in adolescents with low to moderate myopia after wearing the lens for 6 months.Methods:The data of 69 adolescents with low to moderate myopia were retrospectively analyzed.According to the degree of spherical power before treatment,the adolescents were divided into a low myopia group(34 cases,with spherical diopter from-3.00 to-0.75 D)and a moderate myopia group(35 cases,with spherical diopter from-5.75 to-3.25 D).The changes of the uncorrected distance visual acuity(UDVA),intraocular pressure,count of endothelial cell,eye axis length,Strehl ratio(SR),modulation transfer function(MTF),Q value,and wavefront aberrations before the treatment and 6 months after the treatment were compared and analyzed between the 2 groups.Results:Compared with before the treatment,the UDVA improved significantly in the 2 groups(both P<0.05);the intraocular pressure and the count of endothelial cell did not change obviously in the 2 groups(all P>0.05),the eye axial length in the 2 groups was increased significantly(both P<0.05),but there was no significant difference between the 2 groups(all P>0.05);the Q value in the 2 groups was increased significantly,and the change was more obvious for the moderate myopia group(all P<0.05);the SR and MTF were increased remarkably in the 2 groups(all P<0.05),and there were no significant difference in the changes of SR and MTF between the 2 groups(both P>0.05);a considerable decrement was found for the total aberration,the total low-order aberration,and defocus(all P<0.05),and the changes were more significant in the moderate myopia group(all P<0.05);the total high-order aberrations were increased in the low myopia group(P<0.05);the increment of the vertical astigmatism,spherical aberration,horizontal coma,vertical coma,and horizontal trefoil were noticeable(all P<0.05),and the changes of the spherical aberration,vertical coma,and horizontal trefoil were more obvious in the moderate myopia group(all P<0.05).Conclusion:Orthokeratol

关 键 词：低中度近视 角膜塑形镜 视力 眼压 内皮细胞计数 视觉质量 像差 

分 类 号：R778.11[医药卫生—眼科]