普济消毒饮加减治疗疱疹性咽炎60例临床观察  

Clinical observation of Puji Xiaodu decoction in treating 60 casesof herpetic pharyngitis

作　　者：常玉双[1] Chang Yushuang

机构地区：[1]北京市昌平区中医医院,北京102200

出　　处：《中医临床研究》2020年第24期46-48,57,共4页Clinical Journal Of Chinese Medicine

摘　　要：目的:通过中西医两种治疗方法,观察普济消毒饮加减治疗疱疹性咽炎的临床疗效。方法:选取2017年9月-2019年6月在北京市昌平区中医医院确诊的120例疱疹性咽炎患者按照组间匹配原则随机分为两组,治疗组60例给予普济消毒饮基本方加减治疗,临床根据小儿年龄体质量以及伴随症状可随症加减并适当调整剂量,每日1剂,水煎煮200 mL,分两次温服;对照组60例给予对症治疗,干扰素α喷雾或雾化,利巴韦林颗粒口服,每天每公斤10~15 mg,分3次口服,连用3 d,并注意其不良反应,合并细菌感染者加用头孢类抗生素,保持患儿安静,有惊厥病例需及时止惊,地西泮缓慢静脉注射,每千克体重每次服0.3~0.5 mg剂量,注射速度每分钟1~2 mg,每次最大剂量不超过10 mg。并严密监测生命体征,必要时呼吸支持。两组均5 d为1个疗程,疗程结束后,统计临床症状的变化。结果:治疗组在主要症状以及总体疗效上均明显优于对照组,其中主要症状口腔疱疹、发热、呕吐、厌食、流涎、咽痛、烦躁不安,治疗组总有效率为96.7%(58/60),对照组总有效率为75%(45/60)。结论:普济消毒饮加减治疗疱疹性咽炎相对于现代医学常规抗病毒治疗,无论从主要症状,还是从总体疗效,都具有显著的优势。Objective:The clinical efficacy of Puji Xiaodu decoction(普济消毒饮)in the treatment of herpetic pharyngitis was observed by applying two treatment methods:traditional Chinese medicine and western medicine.Methods:120 patients with herpes pharyngitis were randomly divided into two groups according to the principle of matching between groups,60 cases of the treatment group were treated with Modified Puji Xiaodu decoction.The dosage can be adjusted according to children's age,weight and accompanying symptoms,one dose daily,200ml water decoction was divided into two warm doses;60 cases of the control group were treated with symptomatic treatment of Interferon,spray or atomization,and Ribavirin granules were taken orally for 10-15 mg/(kg•d),3 times/day and for 3 continuous days.Attention was given to its adverse reaction and cephalosporin antibiotics could be used if it was complicated with bacterial infection.The children should be kept quiet,shock should be stopped in time in cases of convulsion with slow intravenous injection of Diazepam,0.3-0.5 mg/(kg),injection speed was 1-2 mg,and the maximum dose was not more than 10 times.And the vital signs should be closely monitored,breathing support would be given if it was necessary.Both groups were treated for 5 days,which was a course of treatment.After treatment,the statistical changes of clinical symptoms were counted.Results:The main symptoms,such as oral herpes,fever,vomiting,anorexia,salivation,pharynx pain and irritability were better than the control group.And efficinecy in the treatment group was 96.7%(58/60),better than 75.0%(45/60)in the control group.Conclusion:Compared with modern medicine routine antiviral treatment,Modified Puji Xiaodu decoction treatment of herpes pharyngitis has a significant advantage,it is worthy of clinical promotion from the perspective of either the main symptoms or the overall efficacy.

关 键 词：普济消毒饮 临床观察 疱疹性咽炎 

分 类 号：R[医药卫生]