儿童多系统炎症综合征的临床研究现状与防治方向  

Multisystem inflammatory syndrome in children:its current situation and potential direction in prevention and treatment

作　　者：李谷雨 张若旸 庞明樊 梁作如 杨昕娉 武洁雯 李中杰[4] 刘钢[5] 宋蕊[6] 丁洁[7] 王荃[8] 戚晓鹏[1] 钱素云[9] Li Guyu;Zhang Ruoyang;Pang Mingfan;Liang Zuoru;Yang Xinping;Wu Jiewen;Li Zhongjie;Liu Gang;Song Rui;Ding Jie;Wang Quan;Qi Xiaopeng;Qian Suyun(Center for Global Public Health,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Department of Immunology,School of Basic Medical Sciences,Capital Medical University,Beijing 100069,China;National Institute for Nutrition and Health,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Division of Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Department of Infectious Diseases,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Center of Infectious Diseases,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Department of Pediatrics,Peking University First Hospital,Beijing 100034,China;Department of Emergency,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Pediatric Intensive Care Unit,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China)

机构地区：[1]中国疾病预防控制中心全球公共卫生中心,北京102206 [2]首都医科大学基础医学院免疫学系,北京100069 [3]中国疾病预防控制中心营养与健康所,北京100050 [4]中国疾病预防控制中心传染病管理处,北京102206 [5]国家儿童医学中心,首都医科大学附属北京儿童医院感染内科,100045 [6]首都医科大学附属北京地坛医院感染科,100015 [7]北京大学第一医院儿科,100034 [8]国家儿童医学中心,首都医科大学附属北京儿童医院急诊科,100045 [9]国家儿童医学中心,首都医科大学附属北京儿童医院重症医学科,100045

出　　处：《中华儿科杂志》2020年第9期780-783,共4页Chinese Journal of Pediatrics

基　　金：国家重点研发计划(2020YFC0846300)。

摘　　要：儿童多系统炎症综合征于2020年4月首先由英国儿科医生报道,患儿的临床表现类似川崎病且合并多器官功能损伤。该病多见于6~15岁,黑种人和白种人为主,部分患儿2019新型冠状病毒(2019-nCoV)核酸或血清学抗体检测呈阳性结果,或曾与2019-nCoV感染者有密切接触。发病机制尚不清楚,可能与2019-nCoV感染后引起的异常免疫反应相关。经过以抗炎药物为主的综合治疗后整体预后良好。应继续对儿童2019-nCoV感染常态化防控,推进儿童多系统炎症综合征的基础和临床研究,加强宣传教育,提高我国儿科医生对该病的认识。

关 键 词：儿科医生 异常免疫反应 川崎病 预后良好 抗炎药物 阳性结果 多器官功能损伤 综合治疗 

分 类 号：R725.6[医药卫生—儿科]