经鼻高流量湿化氧疗对急性中重度脑卒中患者临床病情、预后的影响研究  

Effect of nasal high-flow humidified oxygen therapy on the clinical condition and prognosis of patients with acute moderate to severe stroke

作　　者：贝朝昌 王喜江 张丹萍 张和耀[1] 庄承林 Bei Chaochang;Wang Xijiang;Zhang Danping;Zhang Heyao;Zhuang Chenglin(Department of Neurology,Puning Overseas Chinese Hospital,Jieyang,Guangdong,515300,China)

机构地区：[1]普宁华侨医院神经内科,广东揭阳515300

出　　处：《当代医学》2020年第29期12-14,共3页Contemporary Medicine

基　　金：揭阳市科技计划项目(2019ws004)。

摘　　要：目的探究经鼻高流量湿化氧疗对急性中重度脑卒中患者临床病情、预后的影响。方法选取2018年6月至2019年6月本院收治的79例中重度脑卒中患者为研究对象,随机分为观察组(n=38)和对照组(n=41)。观察组采用经鼻高流量湿化氧疗治疗,对照组采用普通鼻导管吸氧治疗,比较两组治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、斯堪地那维亚卒中量表(SSS)评分、格拉斯哥昏迷评分(GCS)、日常生活能力量表(Barthel)指数及动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)等指标变化情况。结果治疗后,观察组NIHSS评分显著低于对照组(P<0.05);观察组SSS、GCS评分、Barthel指数显著高于对照组(P<0.05);观察组PaO2显著高于对照组(P<0.05),PaCO2显著低于对照组(P<0.05)。结论与常规鼻导管氧疗相比,经鼻高流量湿化氧疗可减少患者神经功能损伤,促进脑部功能和意识恢复,增强日常生活自理能力,改善血气指标,从而改善患者预后。Objective To explore the effect of nasal high-flow humidified oxygen therapy on the clinical condition and prognosis of patients with acute and severe stroke.Methods 79 patients with moderate to severe stroke admitted to our hospital from June 2018 to June 2019 were selected as the research subjects,and randomly divided into the observation group(n=38)and control group(n=41).The observation group was treated with nasal high-flow humidified oxygen therapy,and the control group was treated with ordinary nasal catheter oxygen inhalation.Before and after treatment,the National Institutes of Health Stroke Scale(NIHSS),Scandinavian Stroke Scale(SSS),Glasgow Coma Score(GCS),Daily Living Ability Scale(Barthel)index,arterial blood oxygen partial pressure(PaO2)and arterial blood carbon dioxide partial pressure(PaCO2)were compared between two groups.Results After treatment,the NIHSS score of the observation group was significantly lower than that of the control group(P<0.05),and the SSS,GCS score and Barthel index of the observation group were significantly higher in the control group(P<0.05).PaO2 of the observation group was significantly higher than that of the control group(P<0.05),and PaCO2 was significantly lower than that of the control group(P<0.05).Conclusion Compared with conventional nasal cannula oxygen therapy,nasal high-flow humidified oxygen therapy can reduce patients'nerve function damage,promote brain function and consciousness recovery,enhance daily life self-care ability,improve blood gas indexes,and thus improve patient prognosis.

关 键 词：脑卒中 经鼻高流量湿化吸氧 鼻导管吸氧 神经功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学]