活性银离子抗菌液治疗儿童口腔溃疡临床疗效的研究  

The clinical efficacy study of active silver ion antibacterial liquid in the treatment of children′s oral ulcer

作　　者：杜宁[1] 张哲 周湘[3] 李凯 刘学聪[1] DU Ning;ZHANG Zhe;ZHOU Xiang;LI Kai;LIU Xue-cong(Department of Stomatology, Hebei Children′s Hospital, Shijiazhuang 050031, China;Policy Research Office of Hebei Health Guidance Center, Hebei Health Commission, Shijiazhuang 050000, China;Quality Control Office, Hebei Children′s Hospital, Shijiazhuang 050031, China)

机构地区：[1]河北省儿童医院口腔科,河北石家庄050031 [2]河北省卫生健康委健康河北指导中心政策研究室,河北石家庄050000 [3]河北省儿童医院全面质量控制办公室,河北石家庄050031

出　　处：《河北医科大学学报》2020年第9期1075-1078,共4页Journal of Hebei Medical University

基　　金：河北省医学科学研究课题计划(20190131)。

摘　　要：目的观察活性银离子抗菌液治疗儿童口腔溃疡的临床疗效。方法选取92例口腔溃疡患儿作为研究对象,按随机原则分为试验组和对照组,每组46例。试验组给予活性银离子抗菌液局部治疗,对照组给予康复新液局部治疗,观察2组口腔溃疡治疗效果、止痛时间、溃疡愈合时间、治疗后疼痛程度以及患儿对药物接受的反应程度。结果试验组总体有效率与对照组比较,差异无统计学意义(P>0.05);试验组患儿口腔溃疡的止痛时间比对照组更短,差异有统计学意义(P<0.05);2组口腔溃疡愈合时间,差异无统计学意义(P>0.05);治疗后,试验组与对照组的疼痛程度比较显著下降,差异有统计学意义(P<0.05);试验组患儿对于药物使用的依从性显著优于对照组,差异有统计学意义(P<0.05)。结论活性银离子抗菌液治疗儿童口腔溃疡可促进临床症状改善,加快溃疡愈合,减轻患儿局部疼痛,更适用于儿童,效果显著,值得推广应用。Objective To observe the clinical effect of active silver ion antibacterial liquid in the treatment of children's oral ulcer.Methods A total of 92 children with oral ulceration were selected from our department.The children were divided into experimental group and control group according to the principle of random,and 46 cases in each group.The experimental group was given local treatment with active silver ion antibacterial liquid,while the control group was given local treatment with kangfuxin liquid.The treatment effect,the time of relieveing pain,the healing time of the ulceration,the degree of pain after treatment and the degree of response of the children to the drug were observed.Results Compared with the control group,there was no significant difference in the overall effective rate of the experimental group(P>0.05).The pain relief time of oral ulcer in the experimental group was shorter than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in healing time between two groups(P>0.05).After treatment,the degree of pain in the experimental group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).The compliance of children in the experimental group to drug use was significantly better than that in the control group,the difference was statistically significant(P<0.05).Conclusion The active silver ion antibacterial liquid can promote the improvement of clinical symptoms,accelerate the healing of the ulceration,relieve the local pain of the child,and is more suitable for children,and has remarkable effect and is worthy of popularization and application.

关 键 词：口腔溃疡 体征和症状 抗菌药 

分 类 号：R781.5[医药卫生—口腔医学]