乳腺癌术后辅助化疗对老年患者衰弱、认知功能及生活质量的影响  

Impact of adjuvant chemotherapy on frailty,cognitive function,and quality of life in older patients with breast cancer

作　　者：吴云皓 陈洁[1] WU Yunhao;CHEN Jie(Department of Breast Surgery,West China Hospital of Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院乳腺外科,成都610041

出　　处：《中国普外基础与临床杂志》2020年第9期1175-1179,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省科技计划项目(项目编号:2019YFS0338)。

摘　　要：目的总结术后辅助化疗对老年乳腺癌患者衰弱、认知功能和生活质量影响的研究进展。方法采用文献复习的方法,对相关文献进行综述。结果老年乳腺癌患者很有可能能从术后辅助化疗中获益,术后辅助化疗可能会加重已经处于衰弱状态的老年乳腺癌患者的衰弱情况,但对于健康状态较好的老年乳腺癌患者可能不会受其影响;同时,术后辅助化疗可能不会影响老年乳腺癌患者的认知功能及长期的生活质量。结论老年乳腺癌患者应进行多学科评估,并对其制定个体化治疗方案。Objective To summarize the research progress on the impact of postoperative adjuvant chemotherapy on frailty,cognitive function,and quality of life in older patients with breast cancer.Method Collected literatures about the impact of postoperative adjuvant chemotherapy on frailty,cognitive function,and quality of life in older patients with breast cancer to make an review.Results Elderly breast cancer patients were likely to benefit from postoperative adjuvant chemotherapy without undergoing significant impairment of frailty,cognitive function,and quality of life.However,postoperative adjuvant chemotherapy might cause an aggravation of the frailty in patients who was already with it.Conclusion We should develop personalized treatment plans for elderly breast cancer patients after multidisciplinary assessment.

关 键 词：乳腺癌 老年患者 辅助化疗 衰弱 认知功能 生活质量 综述 

分 类 号：R737.9[医药卫生—肿瘤]