啮齿类动物子宫内膜异位症模型的研究进展  

Research advance of rodent animal endometriosis models

作　　者：时光 赵瑞华[1] SHI Guang;ZHAO Ruihua(Department of Gynecology,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]中国中医科学院广安门医院妇科,北京100053

出　　处：《实验动物科学》2020年第3期73-77,共5页Laboratory Animal Science

基　　金：北京市自然科学基金(NO.7182141)。

摘　　要：子宫内膜异位症为妇科的常见病、多发病。约5%~10%的育龄期女性患有子宫内膜异位症,且达50%的内异症患者合并不孕。子宫内膜异位症的发病机制尚不清楚,阐明子宫内膜异位症的发病机制尤为重要。已有很多报道利用动物模型对子宫内膜异位症的发病机制进行研究。本篇综述主要介绍啮齿类动物子宫内膜异位症的模型建立方法、应用及模型的特点。Endometriosis is the presence of endometrium-like tissue in sites outside the uterine cavity.About 5%-10%reproductive women suffered from endometriosis,and up to 50%endometriosis women suffered from infertility.The pathogenesis of endometriosis still unknown,it is imperative to elucidate the mechanisms of endometriosis.Many animal models have been established to investigate the pathogenesis of endometriosis.The review will introduce the method to establish the rodents models,the application and the feature of the animal models.

关 键 词：子宫内膜异位症 啮齿类动物模型 综述 

分 类 号：R-331[医药卫生]