中医护理杵针疗法对肝肾亏虚型干眼的临床疗效观察  

Clinical observation of nursing of Traditional Chinese Medicine with pestle needle therapy in treatment of dry eye with deficiency of liver and kidney syndrome

作　　者：刘艳霞[1] 刘曼[1] 于波[2] LIU Yanxia;LIU Man;YU Bo(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China)

机构地区：[1]辽宁中医药大学,沈阳110847 [2]辽宁中医药大学附属医院,沈阳110847

出　　处：《中国中医眼科杂志》2020年第7期521-525,共5页China Journal of Chinese Ophthalmology

基　　金：辽宁中医药大学教改课题(XJJGLX2018034)。

摘　　要：目的观察中医护理杵针疗法治疗肝肾亏虚型干眼的临床疗效。方法将72例肝肾亏虚型干眼患者,随机分为对照组36例(70只眼)和观察组36例(72只眼),对照组予0.1%玻璃酸钠滴眼液点眼,观察组在对照组基础上联合杵针疗法进行治疗,均治疗21 d。分别于治疗前和治疗后行泪液分泌试验(SIT)、泪膜破裂时间(BUT)、角膜荧光素染色(FL)、视觉模拟量表(VAS)、汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)检查并记录相关数据,比较2组患者的临床疗效和负性情绪。结果 (1)临床疗效:治疗后,观察组显效38只眼,有效28只眼,无效6只眼;对照组显效23只眼,有效35只眼,无效12只眼,2组间临床疗效比较,具有等级差异(Ζ=-2.528,P=0.011);(2)SIT:观察组治疗前(2.60±0.97)分,治疗后(8.17±3.31)分,差异有统计学意义(t=-16.985,P=0.000);对照组治疗前(2.44±0.79)分,治疗后(6.90±3.32)分,差异有统计学意义(t=-11.501,P=0.000);2组治疗后比较,t=2.275,P=0.024,差异有统计学意义。(3)BUT:观察组治疗前(3.50±1.43)分,治疗后(8.38±3.11)分,差异有统计学意义(t=-13.631,P=0.000);对照组治疗前(3.33±1.32)分,治疗后(6.93±3.27)分,差异有统计学意义(t=-7.997,P=0.000);2组治疗后比较,t=2.702,P=0.008,差异有统计学意义。(4)FL:观察组治疗前(5.85±2.28)分,治疗后(1.60±2.38)分,差异有统计学意义(t=16.395,P=0.000);对照组治疗前(5.59±2.17)分,治疗后(2.41±2.13)分,差异有统计学意义(t=10.833,P=0.000);2组治疗后比较,t=-2.155,P=0.033,差异有统计学意义。(5)VAS:观察组治疗前(5.78±1.55)分,治疗后(2.36±1.15)分,差异有统计学意义(t=17.370,P=0.000);对照组治疗前(5.81±1.33)分,治疗后(3.17±1.06)分,差异有统计学意义(t=14.073,P=0.000);2组治疗后比较,t=-3.096,P=0.003,差异有统计学意义。(6)HAMA:观察组治疗前(18.28±4.93)分,治疗后(8.39±2.82)分,差异有统计学意义(t=16.339,P=0.000);对照组治疗前(19.17±3.82)分,治疗后(1OBJECTIVE To observe the clinical effect of artificial tears combined with pestle needle therapy on dry eye with deficiency of liver and kidney syndrome. METHODS A total of72 dry-eyes patients with liver and kidney deficiency syndrome were randomly and evenly divided into control group(70 eyes) and observation group(72 eyes). The control group was given0.1% sodium hyaluronate eye drops, and the observation group was treated with pestle needle therapy in addition to eye drops and all patients were intervened for 21 days. Before and after treatment, tear secretion test(SIT), breakup time of tear film(BUT), corneal fluorescein staining(FL), visual analog scale(VAS), Hamilton anxiety scale(HAMA) and Hamilton depression scale(HAMD) were checked and recorded. Clinical efficacy and negative emotions of two groups were compared. RESULTS(1) the total effective rate: In observation group, 38 eyes were markedly improved after treatment group, 28 eyes were effectively improved, 6 eye were ineffective, the total effective rate was 91.67%;In the control group, 23 eyes were markedly effective, 35 eyes were effective, 12 eyes were ineffective, total effective rate was82.86%, difference was statistically significant(Ζ=-2.528, P=0.011).(2) SIT: In the observation group, SIT was 2.60±0.97 points before treatment and 8.17±3.31 points after treatment, the difference was statistically significant(t=-16.985, P=0.000);In the control group, SIT was 2.44±0.79 points before treatment and 6.90±3.32 points after treatment, the difference was statistically significant(t=-11.501, P=0.000);Comparison between the two groups after treatment showed that the difference was statistically significant(t=2.275, P=0.024).(3) BUT: In the observation group, BUT was 3.50 ±1.43 points before treatment and 8.38 ±3.11 points after treatment, the difference was statistically significant(t=-13.631, P=0.000);In the control group, BUT was 3.33±1.32 points before treatment and 6.93 ±3.27 points after treatment, the difference was statistically significant

关 键 词：干眼 人工泪液 杵针疗法 临床疗效 中医护理 

分 类 号：R777.34[医药卫生—眼科]