睡眠剥夺在认知功能障碍发病中的作用机制研究进展  

Research progress on the mechanism of sleep deprivation in the pathogenesis of cognitive dysfunction

作　　者：刘旭珂 侯家保(综述)[1] 夏中元(审校)[1] Liu Xuke;Hou Jiabao;Xia Zhongyuan(Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, China)

机构地区：[1]武汉大学人民医院麻醉科,430060

出　　处：《疑难病杂志》2020年第9期958-962,共5页Chinese Journal of Difficult and Complicated Cases

基　　金：中央高校基本科研业务费专项基金(2042019kf0061)。

摘　　要：睡眠剥夺(SD)是由于昼夜节律紊乱和睡眠稳态失衡造成的严重睡眠障碍,是当今社会常见问题。许多流行病学和临床研究已将睡眠剥夺与认知功能障碍的发生联系起来,但其相关机制还有待进一步明确。文章就睡眠剥夺在认知功能障碍发病中的作用机制进行综述。Sleep deprivation(SD)is a serious sleep disorder caused by circadian rhythm disturbance and sleep homeostasis.It is a common problem in today's society.Many epidemiological and clinical studies have linked sleep deprivation with the occurrence of cognitive dysfunction,but its related mechanisms need to be further clarified.This article reviews the mechanism of sleep deprivation in the pathogenesis of cognitive dysfunction.

关 键 词：睡眠剥夺 认知功能障碍 作用机制 综述 

分 类 号：R74[医药卫生—神经病学与精神病学]