Genome-wide characterization and developmental expression profiling of long non-coding RNAs in Sogatella furcifera  

作　　者：Zhao-Xia Chang Olugbenga Emmanuel Ajayi Dong-Yang Guo Qing-Fa Wu 

机构地区：[1]Hefei National Laboratory for Physical Sciences at Microscale,School of Life Sciences,University of Science and Technology of China,Hefei,China and [2]CAS Key Laboratory of Innate Immunity and Chronic Disease,University of Science and Technology of China,Hefei,China

出　　处：《Insect Science》2020年第5期987-997,共11页昆虫科学（英文版）

基　　金：This work was supported by the Strategic Priority Re-search Program of the Chinese Academy of Sciences(Grant XDB11040400);the National Natural Science Foundation of China(Grants 31571305,31871927).The funders played no role in the study design,data collection and analysis,decision to publish,or preparation of the manuscript.

摘　　要：The genome-wide characterization of long non-coding RNA(lncRNA)in insects demonstrates their importance in fundamental biological processes.Esentially,an in-depth understanding of the functional repertoire of lncRNA in insects is pivotal to insect resources utilization and sustainable pest control.Using a custom bioinformatics pipeline,we identified 1861 lncRNAs encoded by 1852 loci in the Sogatella furcifera genome.We profiled lncRNA expression in different developmental stages and observed that the expression of lncRNAs is more highly temporally restricted compared to protein-coding genes.More up-re gulated Sogatella furcifera lncRNA expressed in the embryo,4th and 5th instars,suggesting that increased lncRNA levels may play a role in these developmental stages.We compared the relationship between the expression of Sogatella furcifera lncRNA and its nearest protein gene and found that lncRNAs were more correlated to their downstream coding neighbors on the opposite strand.Our genome-wide profiling of lncRNAs in Sogatella furcifera identifies exciting candidates for characterization of lncRNAs,and also provides information on lncRNA regulation during insect development.

关 键 词：CO-EXPRESSION long non-coding RNAs REGULATION RNA-SEQ Sogatella furcifera 

分 类 号：Q96[生物学—昆虫学]