Glisson蒂横断式肝切除术与Pringle法肝切除术治疗对肝细胞癌患者疗效及肝功能的影响  

Curative Effect of Glisson Pedicle Transection Method for Hepatectomy and Pringle Method for Hepatectomy on Patients with Hepatocellular Carcinoma and the Effect on Liver Function

作　　者：胡方彬 卿强 HU Fangbin;QING qiang(Ziyang People's Hospital,Ziyang,641300)

机构地区：[1]资阳市人民医院,641300

出　　处：《实用癌症杂志》2020年第9期1516-1519,共4页The Practical Journal of Cancer

摘　　要：目的探讨Glisson蒂横断式肝切除术与第一肝门阻断(Pringle法)肝切除术治疗对肝细胞癌(HCC)患者疗效及肝功能的影响。方法选取确诊HCC行肝切除术的50例患者,按肝血流阻断术分为G组(Glisson蒂横断式肝切除术,28例)与P组(Pringle法肝切除术,22例)。比较两组围术期指标、术前及术后3 d、术后7 d肝功能指标变化、术后并发症发生率。结果两组术中阻断时间、手术时间及手术后TBIL、ALB指标比较差异无统计学意义(P>0.05);G组术中出血量、输血率及住院时间均小于P组,术后3 d、7 d G组ALT、AST水平显著低于P组,G组并发症发生率显著低于P组(P<0.05)。结论HCC患者应用Glisson蒂横断式肝切除术可减轻肝脏缺血-再灌注损伤程度,术后肝功能恢复较好,术后并发症风险低,值得临床推广。Objective To investigate the curative effect of Glisson pedicle transection method for hepatectomy and the first portal occlusion(Pringle method)for hepatectomy on patients with hepatocellular carcinoma(HCC)and the effect on liver function.Methods 50 patients with HCC who underwent hepatectomy were selected.They were divided into G group(Glisson pedicle transection method for hepatectomy,28 cases)and P group(Pringle method for hepatectomy,22 cases)according to the method for hepatic vascular exclusion.Perioperative indexes,changes in liver function indexes before operation and at 3d and 7d after operation,the incidence of postoperative complications were compared between the two groups.Results There was no significant difference in intraoperative cross-clamp time,operative time,postoperative TBIL or ALB(P>0.05).The intraoperative blood loss,blood transfusion rate and hospitalization time of G group were less/lower/shorter than those of P group.The levels of ALT and AST in G group at 3d and 7d after operation were significantly lower than those in P group.The incidence of complications in G group was significantly lower than that in P group(P<0.05).Conclusion The application of Glisson pedicle transection method for hepatectomy of patients with HCC can relieve the degree of liver ischemia reperfusion injury.The postoperative liver function recovery is good and the risk of postoperative complications is low.

关 键 词：Glisson蒂横断式肝切除术 第一肝门阻断肝切除术 肝细胞癌 肝功能 

分 类 号：R734.2[医药卫生—肿瘤]