网状Meta分析证据质量分级:CINeMA在线应用程序简介  

Rating the certainty of evidence from network meta-analysis:an introduction to CINeMA

作　　者：王琪 王韵华 赖鸿皓 王琦 丁国武[2] 田金徽[3,4] 陈耀龙 杨克虎[3,4] 吴大嵘 郭新峰[5] 杨丽虹 葛龙[1,2,4] WANG Qi;WANG Yunhua;LAI Honghao;WANG Qi;DING Guowu;TIANJinhui;CHEN Yaolong;YANG Kehu;WU Darong;GUO Xinfeng;YANG Lihong;GE Long(Evidence-Based Social Science Research Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Department of Social Science and Health Management,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Evidence-Based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,P.R.China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine/Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,P.R.China)

机构地区：[1]兰州大学公共卫生学院循证社会科学研究中心,兰州730000 [2]兰州大学公共卫生学院社会医学与卫生事业管理研究所,兰州730000 [3]兰州大学基础医学院循证医学中心,兰州730000 [4]甘肃省循证医学与临床转化重点实验室,兰州730000 [5]广州中医药大学第二附属医院/广东省中医院,广州510120

出　　处：《中国循证医学杂志》2020年第9期1111-1116,共6页Chinese Journal of Evidence-based Medicine

基　　金：国家重点研发计划资助项目(编号:2019YFC1709805)。

摘　　要：因网状Meta分析(NMA)的证据质量分级极其复杂和耗时,为帮助研究者更好掌握NMA的证据质量分级,本文介绍了一个基于GRADE方法的在线网状Meta分析证据分级应用程序—CINeMA。该应用程序主要基于网状Meta分析的贡献矩阵结果,从以下6个领域对NMA证据质量进行评估:研究内偏倚、研究间偏倚、间接性、不精确性、异质性和不一致性。It is a complex and time-consuming process to rate the certainty(quality) of evidence from network meta-analysis. This paper aims to introduce a web application for rating the certainty of network meta-analysis-the CINeMA. CINeMA is based on GRADE framework and contribution matrix of network meta-analysis, which considers 6 domains including within-study bias, across-studies bias, indirectness, imprecision, heterogeneity, and incoherence.

关 键 词：网状Meta分析 CINeMA应用程序 证据质量 

分 类 号：R-03[医药卫生]