复杂后循环颅内段动脉粥样硬化性病变的诊疗进展  

Progress in Diagnosis and Treatment of Complex Intracranial Posterior Circulation Atherosclerosis Lesions

作　　者：徐子奇[1] XU Zi-Qi(Department of Neurology,The First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China)

机构地区：[1]浙江大学医学院附属第一医院神经内科,杭州310003

出　　处：《中国卒中杂志》2020年第10期1123-1127,共5页Chinese Journal of Stroke

基　　金：浙江省科技厅基础公益研究计划(LGF20H090010)。

摘　　要：中国是颅内动脉粥样硬化疾病的高发地区,多种危险因素与之有关。前后循环颅内动脉狭窄/闭塞在危险因素分布上存在一定的差异性,同时后循环动脉的解剖结构具有自身独特的特点且具有较多的解剖变异性。本综述回顾了基于颅内动脉粥样硬化的Mori分型、LMA分型,并对复杂后循环颅内段动脉粥样硬化性病变进行了临床定义。由于复杂后循环颅内段动脉粥样硬化性病变药物治疗效果往往不佳,卒中复发率高,同时血管内治疗又较困难,因此,本文从解剖结构、危险因素、卒中病理生理特点、侧支循环、影像学评估及临床治疗进展多个方面对复杂后循环病变进行了综述。The incidence of intracranial atherosclerosis diseases(IAD)is high in Chinese people,and many risk factors are associated with IAD.The risk factors are different between anterior and posterior circulation IAD,meanwhile,the posterior circulation artery has its own unique anatomical characteristics and more variability.In this article the complex vertebrobasilar atherosclerotic lesions were defined referring to intracranial atherosclerotic lesions Mori type and LMA classification.However,for the patients with complex posterior circulation lesions,medical treatment is usually poor and endovascular therapy is usually difficult,and with a high rate of stroke recurrence.Therefore,this article reviewed the progress of the complex posterior circulation lesions from different aspects such as anatomy characteristics,risk factors,stroke pathophysiology,collateral circulation,imaging evaluation and clinical treatment.

关 键 词：缺血性卒中 动脉粥样硬化 椎基底动脉 血管内治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]