核基质结合区结合蛋白质1介导Snail/Slug信号通路调控上皮-间充质转化评估直肠癌分子切缘的研究  

Experimental study on the molecular margin of rectal cancer by regulating epithelial mesenchymal transition mediated by snail/slug signaling pathway mediated by special AT rich sequence binding protein-1

作　　者：李彦 潘烽平 彭勃 李海强 张明明 周莉 Li Yan;Pan Fengping;Peng Bo;Li Haiqiang;Zhang Mingming;Zhou Li(Department of Anorectal,Jiaxing First Hospital and the Affiliated Hospital of Jiaxing University,Jiaxing 314000,China)

机构地区：[1]嘉兴市第一医院暨嘉兴学院附属医院肛肠外科,314000

出　　处：《中华实验外科杂志》2020年第7期1354-1354,共1页Chinese Journal of Experimental Surgery

基　　金：浙江咨医药卫生科研面上项目(2O18KY797);嘉兴市科技局科技汁划项目(2019AD32258)。

摘　　要：我们收集80例直肠癌患者的临床资料及组织标本,通过核基质结合区结合蛋白质1(SATB1)介导Sriail/Slug信号通路调控上皮间充质分析直肠癌环周切缘及下切缘肿瘤微转移与预后相关性,探讨SATB1介导Snail/Slug信号通路调控上皮间充质转化评估直肠癌分子切缘的指导价值[1]。

关 键 词：上皮间充质转化 分子切缘 下切缘 肿瘤微转移 环周切缘 间充质 直肠癌患者 SATB1 

分 类 号：R735.37[医药卫生—肿瘤]