Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients  被引量:6

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作  者:Bao-zhong Zhang Ye-fan Hu Lin-lei Chen Thomas Yau Yi-gang Tong Jing-chu Hu Jian-piao Cai Kwok-Hung Chan Ying Dou Jian Deng Xiao-lei Wang Ivan Fan-Ngai Hung Kelvin Kai-Wang To Kwok Yung Yuen Jian-Dong Huang 

机构地区:[1]CAS Key Laboratory of Quantitative Engineering Biology,Shenzhen Institute of Synthetic Biology,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China [2]School of Biomedical Sciences,Li Ka Shing Faculty of Medicine,University of Hong Kong,3/F,Laboratory Block,21 Sassoon Road,Hong Kong,China [3]Department of Medicine,University of Hong Kong,4/F Professional Block,Queen Mary Hospital,102 Pokfulam Road,Hong Kong,China [4]Department of Microbiology,University of Hong Kong,19/F T Block,Queen Mary Hospital,102 Pokfulam Road,Hong Kong,China [5]Beijing Advanced Innovation Centre for Soft Matter Science and Engineering(BAIC-SM),College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China

出  处:《Cell Research》2020年第8期702-704,共3页细胞研究(英文版)

基  金:This work was supported by Health and Medical Research Fund(COVID190117)from the Government of the Hong Kong Special Administrative Region,the Shenzhen Peacock Team Project(KQTD2015033117210153);Shenzhen Science and Technology Innovation Committee Basic Science Research Grant(JCYJ20170413154523577);China Postdoctoral Science Foundation(2019M663167).

摘  要:Dear Editor,The ongoing coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2(SARSCoV-2)is a serious threat to global public health,and is imposing severe burdens on human society.Several candidate vaccines against SARS-CoV-2 are now undergoing clinical trials.The Spike(S)protein of SARS-CoV-2 is widely considered as a promising antigen.However.

关 键 词:ACUTE RESPIRATORY CLINICAL 

分 类 号:R563.1[医药卫生—呼吸系统]

 

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