行内镜逆行性胰胆管造影术治疗急性胆源性胰腺炎疗效观察与安全性分析  

Endoscopic Retrograde Cholangiopancreatography in the Treatment of Acute Biliary Pancreatitis:Efficacy Observation and Safety Analysis

作　　者：钟灿新 许哲[1] ZHONG Can-xin;XU Zhe(Department of Gastroenterology,Dongguan People's Hospital,Dongguan,Guangdong Province,523059 China)

机构地区：[1]东莞市人民医院消化内科,广东东莞523059

出　　处：《中外医疗》2020年第23期72-74,共3页China & Foreign Medical Treatment

摘　　要：目的探讨经内镜逆行性胰胆管造影术(ERCP)治疗急性胆源性胰腺炎(ABP)的效果与安全性。方法便利选取2017年11月-2019年11月该院收治的110例ABP患者为观察对象,按照治疗方法不同分为对照组(n=55,给予内科保守治疗)及观察组(n=55,在对照组基础上采取ERCP治疗)。观察两组治疗前后C反应蛋白(CRP)、降钙素元(PCT)变化情况,比较两组的并发症发生率。结果两组患者治疗前的CRP、PCT水平差异无统计学意义(P>0.05),治疗后两组患者的指标均有改善,但观察组CRP、PCT水平低于对照组(P<0.05);观察组的并发症发生率为3.64%,明显低于对照组的14.55%(χ^2=3.960,P<0.05)。结论ERCP治疗可有效减轻ABP患者的炎症反应,降低并发症发生率,有利于促进疾病尽早痊愈。Objective To investigate the efficacy and safety of endoscopic retrograde cholangiopancreatography(ERCP)in the treatment of acute biliary pancreatitis(ABP).Methods 110 patients with ABP admitted in the hospital from November 2017 to November 2019 were convenient selected as observation objects,and were divided into a control group(n=55,conservative medical treatment)and an observation group(n=55,based on the control group added ERCP treatment.Observe the changes of C-reactive protein(CRP)and calcitonin(PCT)before and after treatment in the two groups,and compare the incidence of complications between the two groups.Results The CRP and PCT levels of the two groups of patients before treatment were not significantly different(P>0.05),and the indexes of the two groups of patients improved after treatment,but the CRP and PCT levels of the observation group were lower than those of the control group(P<0.05);The incidence of complications was 3.64%,which was significantly lower than 14.55%of the control group(χ^2=3.960,P<0.05).Conclusion ERCP treatment can effectively reduce the inflammatory response of ABP patients,reduce the incidence of complications,and help promote the early recovery of the disease.

关 键 词：内镜 逆行性胰胆管造影术 急性胆源性胰腺炎 C反应蛋白 降钙素元 

分 类 号：R576[医药卫生—消化系统]