2004—2016年广州市食管癌发病趋势分析  

Analysis of Incidence Trend of Esophageal Cancer in Guangzhou from 2004 to 2016

作　　者：李科[1] 林国桢[1] 许欢[1] 李燕[1] 梁颖茹[1] 董航[1] LI Ke;LIN Guo-zhen;XU Huan;LI Yan;LIANG Yin-ru;DONG Hang(Guangzhou Center of Disease Control and Prevention,Guangzhou 510440,China)

机构地区：[1]广州市疾病预防控制中心,广东广州510440

出　　处：《中国肿瘤》2020年第9期672-676,共5页China Cancer

摘　　要：[目的]分析2004—20016年广州市居民食管癌发病趋势。[方法]根据广州市肿瘤登记处收集的2004—20016年广州市食管癌的病例资料,计算、分析分年和分地区粗发病率、2000年中国人口标化发病率(中标率)、Segi’s世界人口标化发病率(世标率)和发病年度变化率百分比(APC),利用Jointpoint回归分析各性别和地区变化趋势。[结果]2016年广州市户籍居民新发病例498例,男、女性世标率之比为7.31∶1(男性6.43/10万,女性0.88/10万)。男、女性食管癌发病粗率、世标率均呈下降趋势,世标率女性(APC=-8.85%,95%CI:-10.40%^-7.30%)较男性(APC=-4.46%,95%CI:-5.40%^-3.50%)下降速度更快(P=0.04)。城区、郊区、郊县发病变化差异较大,城区世标率(APC=-7.68%,95%CI:-9.80%^-5.50%)下降最多,郊区粗率未有变化(APC=0.14%,95%CI:-1.00%~1.30%),郊县粗率(APC=4.30%,95%CI:1.20%~7.00%)呈上升趋势。[结论]广州市食管癌低于全国平均水平,但郊县食管癌发病率呈上升趋势,应加强对郊县食管癌的防治。[Purpose]To analyze the incidence trends of esophageal cancers in Guangzhou from2004 to 2016.[Methods]The crude incidence,age-stardardized incidence rates by China population 2000(ASR-C),by Segi’s world standard population(ASR-W)and annual percent change(APC)were calculated by analyzing data obtained from Guangzhou Cancer Registration Center.Time trends of different gender and regions were examined using Jointpoint Regression Program.[Results]Altogether 498 new cases of esophageal cancers were registered in 2016 and the sex ratio of male to female ASR-W was 7.31∶1(6.43/10~5 in male,0.88/10~5 in female).The decreasing trends were seen in the crude and age-adjusted incidence rate of esophageal cancer in both male and female,and the age-adjusted rate in female(APC=-8.85%,95%CI:-10.40%^-7.30%)decreased faster than that in male(APC=-4.46%,95%CI:-5.40%^-3.50%)(P=0.04).The incidence trends were different in urban,suburban and county areas with the largest decline in urban areas for ASR-W(APC=-7.68%,95%CI:-9.80%^-5.50%),remaining unchanged in suburban areas for crude incidence(APC=0.14%,95%CI:-1.00%~1.30%)and showing an upward trend in county areas for crude incidence(APC=4.30%,95%CI:1.20%~7.00%).[Conclusion]The esophageal cancer incidence rate of Guangzhou is lower than the average level in China,but there is an upward trend in county areas,so the prevention and treatment should be strengthened in county areas.

关 键 词：发病率 食管癌 趋势 广东 

分 类 号：R73-31[医药卫生—肿瘤] R735.1[医药卫生—临床医学]