人工假体置换与瘤段切除灭活再植治疗老年股骨近段恶性骨肿瘤的临床应用对比分析  

Comparison on clinical application value of artificial prosthesis replacement and enbolc resection and inactivation and replantation in the treatment of elderly patients with malignant bone tumors in the proximal femur

作　　者：常春峰 荔琦 杨进 CHANG Chunfeng;LI Qi;YANG Jin(Department of Bone Trauma,Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang 712000,Shaanxi,China)

机构地区：[1]陕西中医药大学附属医院骨创伤科,陕西咸阳7120000

出　　处：《癌症进展》2020年第18期1913-1915,1944,共4页Oncology Progress

摘　　要：目的比较人工假体置换与瘤段切除灭活再植治疗老年股骨近段恶性骨肿瘤的临床应用价值。方法根据手术治疗方法的不同将84例老年股骨近段恶性骨肿瘤患者分为观察组和对照组,每组42例,观察组患者接受瘤段切除灭活再植治疗,对照组患者接受人工假体置换治疗。比较两组患者的临床疗效、并发症发生情况及术后6个月的生活质量。结果观察组患者的总有效率为78.57%,明显高于对照组的61.90%,差异有统计学意义(P﹤0.01)。观察组患者的并发症总发生率为16.67%,低于对照组的35.71%,差异有统计学意义(P﹤0.05)。术后6个月,观察组患者的躯体功能、角色功能、情感功能、认知功能、社会功能及总体健康状态评分均明显高于对照组,差异均有统计学意义(P﹤0.01)。结论与人工假体置换相比,瘤段切除灭活再植治疗老年股骨近段恶性骨肿瘤的临床疗效较好,并发症发生率较低,且术后患者的生活质量较高,值得临床推广。Objective To compare the clinical application value of artificial prosthesis replacement and enbolc resection and inactivation and replantation in the treatment of elderly patients with malignant bone tumors in the proximal femur.Method A total of 84 elderly patients with malignant bone tumors in the proximal femur were selected and divided into observation group and control group according to different therapeutic regimens with 42 cases in each group.The observation group was treated with enbolc resection and inactivation and replantation,while the control group was treated with artificial prosthesis replacement.The clinical efficacy,incidence of complications and the quality of life at 6 months after surgery were compared between the two groups.Result The overall response rate of the observation group was 78.57%,which was significantly higher than 61.90%of the control group,the difference was statistically significant(P<0.01).The total incidence of complications in the observation group was 16.67%,which was lower than 35.71%in the control group,the difference was statistically significant(P<0.05).At 6 months after surgery,the scores of physical function,role function,emotional function,cognitive function,social function and general health status of the observation group were significantly higher than those of the control group,and the differences were statistically significant(P<0.01).Conclusion Compared with artificial prosthesis replacement,enbolc resection and inactivation and replantation is a regimen that indicating better clinical effects,lower complication rate,and higher quality of life for the treatment of elderly patients with malignant tumors in the proximal femur,and is worthy of clinical promoting.

关 键 词：人工假体置换 瘤段切除灭活再植 老年 股骨近段恶性骨肿瘤 

分 类 号：R738.1[医药卫生—肿瘤]