大气污染与缺血性脑卒中相关性的研究进展  

Research progress on the association between air pollution and cerebral ischemic strokes

作　　者：李中中 布凯林 秦晋 张荣[2] 刘晓云[1,3,4] Li Zhongzhong;Bu Kailin;Qin Jin;Zhang rong;Liu Xiaoyun(Department of Neurology,Second Hospital of Hebei Medical University,Shijiazhuang 050000,China;Department of Toxicology,the School of Health,Hebei Medical University,Shijiazhuang 050000,China;Key Laboratory of Neurology in Hebei,Shijiazhuang 050000,China;Neuroscience Research Center,Medicine and Health Institute,Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院神经内科,石家庄050000 [2]河北医科大学公共卫生学院卫生毒理教研室,石家庄050000 [3]河北省神经病学重点实验室,石家庄050000 [4]河北医科大学医学健康研究神经中心,石家庄050000

出　　处：《中华脑血管病杂志（电子版）》2020年第4期199-203,共5页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

基　　金：国家自然科学基金项目(81571160)。

摘　　要：缺血性脑卒中发病率逐年攀升,伴随而来的是高病死率和高致残率。缺血性脑卒中发病率的升高与人口老龄化、饮食结构改变、气候及环境等多种因素有关。目前越来越多的学者认为大气污染是缺血性脑卒中发生的重要危险因素,但在缺血性脑卒中发生发展的过程中,大气污染与其相关的机制尚未达成统一共识。深入了解大气污染对缺血性脑卒中的影响及其相关机制有助于缺血性脑卒中的预防,促进缺血性脑卒中后神经功能的恢复,改善患者预后。因此,本文对近年来大气污染与缺血性脑卒中相关性及其机制进行了综述。The incidence of cerebral ischemic strokes is annually increasing,with higher and higher mortality and disability.The increasing morbidity of cerebral ischemic strokes is due to various factors such as population aging,changes in diet,climate and environment.At present,more and more researchers believe that the air pollution is an important risk factor for cerebral ischemic strokes.However,the underlying mechanisms between cerebral ischemic strokes and air pollution haven't reached a consensus yet.In-depth understanding of effect of the air pollution on cerebral ischemic strokes and its related mechanisms can help to prevent cerebral ischemic stroke,restore neurological function,and improve the prognosis of patients with cerebral ischemic strokes.Therefore,we reviewed the correlation between air pollution and cerebral ischemic strokes in recent years.

关 键 词：大气污染 缺血性脑卒中 颗粒性污染物2.5 颗粒性污染物10 二氧化氮 二氧化硫 

分 类 号：R743.3[医药卫生—神经病学与精神病学]