液基细胞学及高危型HPV联合应用在宫颈癌筛查中的临床价值  

The clinical value of combined application of liquid-based cytology and high-risk HPV in cervical cancer screening

作　　者：田维莉[1] 陈昌荣 Tian Weili;Chen Changrong(People's Hospital of Suiyang County, Zunyi, Guizhou 563300)

机构地区：[1]贵州省绥阳县人民医院,贵州遵义563300

出　　处：《中外女性健康研究》2020年第19期69-70,共2页Women＇s Health Research

摘　　要：目的:探讨液基细胞学(TCT)及高危型HPV联合应用在宫颈癌筛查中的临床价值。方法:选择2019年1月至2020年3月在本院接受宫颈癌筛查的2514例患者,均行TCT及高危型HPV检查,以病理组织活检为诊断的金标准,分析其筛查结果。结果:在2514例受检者中,TCT检测异常84例,其中ASC 31例,鳞状上皮内低度病变26例,鳞状上皮内高度病变27例;HPV检测异常363例,低危型80例,高危型283例。CIN及以上病变的检出率随宫颈细胞学病变程度的加重而升高,TCT联合高危HPV更有利于提高宫颈病变检出率。结论:TCT联合高危型HPV可有效确诊宫颈病变,在基层医院宫颈癌筛查中具有较高的应用价值。Objective:To explore the value of combined application of liquid-based cytology(TCT)and high-risk HPV in cervical cancer screening.Methods:2514 patients in our hospital screened for cervical cancer were selected.They all underwent TCT and high-risk HPV examinations,and the screening results were analyzed.Results:Among the selected patients,84 cases were abnormal in TCT detection,including 31 cases of ASC,26 cases of low-grade squamous intraepithelial lesions,27 cases of high-grade squamous intraepithelial lesions,and 363 cases were abnormal in HPV detection,including 80 cases of low-risk type,283 cases of high-risk type.The detection rate of CIN and above lesions increased with the severity of cervical cytological lesions.TCT combined with high-risk HPV was more conducive to increasing the detection rate of cervical lesions.Conclusion:TCT combined with high-risk HPV can effectively diagnose cervical lesions and has high application value in cervical cancer screening in primary hospitals.

关 键 词：TCT 高危型HPV 宫颈癌筛查 病理组织活检 

分 类 号：R73[医药卫生—肿瘤]