Analysis of therapeutic effect of cervical radiofrequency ablation on persistent HR-HPV infection  

作　　者：Wen-Ming Cao Li-Li Yu Xiu-Rong Wang Xin-Ling He Na Yu 

机构地区：[1]Department of Gynecology,Changle People’s Hospital,Changle 262400,China [2]Dezhou Hospital of traditional Chinese Medicine,Dezhou 253000,China [3]Shandong Provincial Third Hospital,Jinan 250000,China

出　　处：《TMR Cancer》2020年第5期221-230,共10页TMR肿瘤

摘　　要：Background:To investigate the therapeutic effect of cervical radiofrequency ablation on high risk-HPV persistent infection.Methods:One hundred patients with persistent high risk-HPV infection diagnosed in our hospital from April 2019 to February 2020 were selected.Those in the same period were randomly selected by SPSS19.0 software machine according to the ratio of 1:1,and divided into the treatment group(BBT-RF-A radiofrequency group)and the observation group(recombinant human interferon suppository group)with 50 cases in each group.The negative conversion rate of high risk-HPV between the 2 groups was compared at the 6th and 12th months after treatment,and the types of persistent HR-HPV infection in Changle were studied.Results:The negative conversion rates of HR-HPV in the treatment group were 60%(35/50)and 82%(41/50)at 6 and 12 months after treatment,respectively,while the negative conversion rates of high risk-HPV in the observation group were 30%(15/50)and 44%(22/50)at 6 and 12 months after treatment,respectively.The negative conversion rates in the treatment group were significantly higher than those in the observation group(P<0.05).Studying the main types of high risk-HPV persistent infection has guiding value for HPV vaccine injection in Changle.Conclusion:Self-clotting cutter radiofrequency ablation has a good effect on the negative conversion rate of high risk-HPV persistent infection.These results suggest that the main types of single persistent cervical HR-HPV infection are 16,52 and 58,not including the 18 types.

关 键 词：BBT-RF-A self-clotting cutter CERVIX HR-HPV Persistent infection 

分 类 号：R73[医药卫生—肿瘤]