Active surveillance as a management strategy for papillary thyroid microcarcinoma  

作　　者：Huan Zhang Xiangqian Zheng Juntian Liu Ming Gao Biyun Qian 

机构地区：[1]Cancer Prevention Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China [2]Department of Head and Neck Tumor,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China [3]Hongqiao International Institute of Medicine,Shanghai Tongren Hospital and Faculty of Clinical Research Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China

出　　处：《Cancer Biology & Medicine》2020年第3期543-554,共12页癌症生物学与医学（英文版）

基　　金：This study was supported by grants from the National Natural Science Foundation of China(Grant No.81602926);the Tianjin Key Research and Development Program Science and Technology Support Key Projects(Grant No.17YFZCSY00690);the Shanghai Health and Family Planning Commission Intelligent Medical Research Project(Grant No.2018ZHYL0202).

摘　　要：Active surveillance(AS)can be considered as a treatment strategy for low risk papillary thyroid microcarcinoma(PTMC),with the absence of clinically apparent lymph nodes,extrathyroidal extensions,and distant metastasis.After reviewing the reports on AS of low risk PTMCs worldwide,we introduced AS,and discussed the selection criteria for active surveillance candidates based on different guidelines and the follow-up schedules.Moreover,the requirement of cytological diagnosis,progression evaluation methods,necessity of thyrotropin suppression,and medical costs were issues that both clinicians and patients considered.The usefulness of AS for low risk PTMC patients depended on accurate and confidential evaluation of patient risk.Clinicians may adopt measures like dynamic monitoring,risk stratification,and making personal follow-up schedules to minimize these potential risks.By appropriately selecting PTMC patients,AS can be an effective alternative treatment to immediate surgery.

关 键 词：Papillary thyroid carcinoma MICROCARCINOMA active surveillance GUIDELINES low risk 

分 类 号：R736.1[医药卫生—肿瘤]