N-烷基化甘氨酸乙酯-吩嗪-1-羧酸衍生物的合成及其抑菌活性  

Synthesis and fungicidal activity of N-alkylated glycine ethyl ester-phenazine-1-carboxylic acid derivatives

作　　者：熊永通 胡津瑜 王云萍 吴清来 李俊凯 XIONG Yong-tong;HU Jin-yu;WANG Yun-ping;WU Qing-lai;LI Jun-kai(College of Agriculture/Institute of Pesticides,Yangtze University,Jingzhou 434025,Hubei,China)

机构地区：[1]长江大学农学院/农药研究所,湖北荆州434025

出　　处：《湖北农业科学》2020年第16期85-87,95,共4页Hubei Agricultural Sciences

基　　金：国家重点研发计划项目(2018YFD0200500);国家自然科学基金项目(31672069)。

摘　　要：为获得高活性的化合物,以吩嗪-1-羧酸为先导化合物,设计合成了6个新型N-烷基化甘氨酸乙酯-吩嗪-1-羧酸衍生物。利用核磁共振氢谱和高分辨质谱对目标化合物进行了结构表征,并对目标化合物进行了抑菌活性测试。结果表明,合成的目标化合物对6种供试真菌都具有一定的抑菌活性。In order to obtain highly active compounds,six novel N-alkylated glycine ethyl ester-phenazine-1-carboxylic acid deriva⁃tives were designed and synthesized using phenazine-1-carboxylic acid as a lead compound.The target compounds were characterized by 1H NMR and HIGH resolution MASS spectrometry.The fungicidal activity of the target compounds was tested.The results showed that the synthesized target compounds had certain fungicidal activity against the six tested fungi.

关 键 词：吩嗪-1-羧酸 N-烷基化甘氨酸乙酯 合成 抑菌活性 

分 类 号：S482.292[农业科学—农药学] O626.417[农业科学—植物保护]