Risk of anemia in morbidly obese patients after bariatric surgery in Taiwan  

作　　者：Tse-Yao Wang Hsien-Hao Huang Ming-Shun Hsieh Chih-Yen Chen 

机构地区：[1]Department of Emergency Medicine,Taipei Veterans General Hospital,Taipei 112,Taiwan [2]College of Medicine,National Yang-Ming University of Medicine,Taipei 112,Taiwan [3]Department of Emergency Medicine,Taipei Veterans General Hospital,Taoyuan Branch,Taoyuan 330,Taiwan [4]Institute of Occupational Medicine and Industrial Hygiene,National Taiwan University College of Public Health,Taipei 112,Taiwan [5]Division of Gastroenterology and Hepatology,Department of Medicine,Taipei Veterans General Hospital,Taipei 112,Taiwan [6]Faculty of Medicine and Institute of Emergency and Critical Medicine,National Yang-Ming University School of Medicine,Taipei 112,Taiwan [7]Chinese Taipei Society for the Study of Obesity,Taipei 110,Taiwan

出　　处：《World Journal of Diabetes》2020年第10期447-458,共12页世界糖尿病杂志（英文版）（电子版）

基　　金：Supported by the Yin Shu-Tien Foundation Taipei Veterans General Hospital-National Yang-Ming University Excellent Physician Scientists Cultivation Program,No.107-V-B-087.

摘　　要：BACKGROUND Bariatric surgery is one of most effective long-term treatments for morbid obesity.However,post-bariatric surgery anemia is identified as a common adverse effect and remains a challenge nowadays.AIM To estimate the risk of post-bariatric surgery anemia and to stratify the association between age,gender,and types of surgery.METHODS This study is a population-based cohort study.We conducted this nationwide study using claims data from National Health Insurance Research Database in Taiwan.There were 4373 morbidly obese patients in this study cohort.RESULTS Among patients who were diagnosed with morbid obesity,2864 received bariatric surgery.All obesity-associated comorbidities decreased in the surgical group.Increasing risk of post-bariatric surgery anemia among obese patients was found by Cox proportional hazards regression[adjusted hazard ratio(HR):2.36].Also,we found significantly increasing cumulative incidence rate of anemia among patients receiving bariatric surgery by log-rank test.After adjusting for age and gender,the increasing incidence of post-bariatric surgery anemia was found among women(adjusted HR:2.48),patients in the 20–29-year-old group(adjusted HR:3.83),and patients in the 30-64-year-old group(adjusted HR:2.37).Moreover,malabsorptive and restrictive procedures had significantly higher adjusted HRs,3.18 and 1.55,respectively.CONCLUSION Bariatric surgery give rise to anemia risk among obese patients,specifically in women,young-and middle-aged patients,and patients undergoing malabsorptive procedures in our population-based cohort study in Taiwan.

关 键 词：ANEMIA Bariatric surgery Malabsorptive procedure OBESITY Restrictive procedure WOMEN 

分 类 号：R656.61[医药卫生—外科学]