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作 者:白雪松 孙德春 宋岩[1] 李银清[1] BAI Xuesong;SUN Dechun;SONG Yan;LI Yinqing(Changchun University of Chinese Medicine,Chanchun 130117,China;Changchun XianYing Medical Technology Co.Ltd.,Changchun 130103,China)
机构地区:[1]长春中医药大学,吉林长春130117 [2]长春先盈医疗科技有限公司,吉林长春130103
出 处:《中国医药指南》2020年第26期8-11,共4页Guide of China Medicine
摘 要:目的评价量子降糖装置对2型糖尿病(T2DM)模型鼠的血糖调节作用。方法采用高脂饮食联合链脲佐菌素诱导糖尿病模型,以量子降糖装置处理,通过检测小鼠体质量、空腹血糖、葡萄糖耐量,采用ELISA试剂盒检测小鼠中血清学生化指标及炎性因子等水平的变化。评价量子降糖装置对糖尿病模型鼠的改善作用。结果量子降糖装置治疗后,常规组和强化组小鼠与模型组相比,强化组体质量和FBG显著降低,糖耐量增强;血清中的TC、TG和LDL水平下降,HDL水平显著升高;血清中的GHbA_1c的生成率降低,GLP-1的含量提高,INS抵抗明显改善;血清中炎性因子水平显著降低。结论量子降糖装置具有辅助降血糖作用,可作为一种安全有效的非药物治疗方法应用于临床。Objective To evaluate the effect of quantum hypoglycemic device on blood glucose regulation in type 2 diabetes(T2DM)model rats.Method Adopt high-fat diet combined with streptozotocin to induce diabetes model,and treat with quantum hypoglycemic device,by detecting the body mass,fasting blood glucose and glucose tolerance of mice,and using ELISA kit to detect serum biochemical indicators and infl ammatory factors in mice level changes.To evaluate the eff ect of quantum hypoglycemic device on diabetic model rats.Results After treatment with the quantum hypoglycemic device,compared with the model group,mice in the conventional group and the intensive group had signifi cantly lower body weight and FBG,and increased glucose tolerance;serum levels of TC,TG,and LDL decreased,and HDL levels increased signifi cantly;the production rate of GHbA1c is reduced,the content of GLP-1 is increased,INS resistance is signifi cantly improved;the level of infl ammatory factors in the serum is signifi cantly reduced.Conclusion The quantum hypoglycemic device has the effect of assisting in lowering blood sugar,and can be used in clinical practice as a safe and effective non-drug treatment.
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