调强放疗同步化疗治疗中晚期食管癌的疗效观察  

Therapeutic Effect of Intensity-modulated Radiotherapy Combined with Chemotherapy in the Treatment of Advanced Esophageal Cancer

作　　者：张思 ZHANG Si(Central Hospital of Yingkou Economic and Technological Development Zone(The Sixth People's Hospital of Yingkou),Yingkou 115007,China)

机构地区：[1]辽宁省营口经济技术开发区中心医院(营口市第六人民医院),辽宁营口115007

出　　处：《中国医药指南》2020年第26期37-38,共2页Guide of China Medicine

摘　　要：目的观察调强放疗同步化疗技术对于中晚期食管癌患者进行治疗的效果分析。方法本文选择的84例研究对象为我院在2017年1月至2018年8月收治的中晚期食管癌患者,按照随机方法将其分为调强放疗组和联合化疗组,每组患者均为42例,对两组患者分别选择采用调强放疗方案和调强放疗同步TP化疗方案进行治疗,比较两组的治疗总有效率、不良反应及生活质量。结果联合化疗组治疗总有效率、生活质量评分明显高于调强放疗组(P <0.05),但两组不良反应发生率无显著差异(P> 0.05)。结论对于中晚期食管癌患者选择调强放疗同步TP方案化疗进行治疗可以显著提高患者治疗有效率,具有较高的安全性,且对改善患者的生活质量也具有重要意义。Objective To observe the eff ect of IMRT and concurrent chemotherapy for patients with advanced esophageal cancer.Methods The 84 study subjects selected in this article are patients with advanced esophageal cancer admitted to our hospital from January 2017 to August 2018.They were divided into intensity-modulated radiotherapy(IMRT)group and combination chemotherapy group according to the random method.For 42 cases,the two groups of patients were treated with IMRT and IMRT-synchronized TP chemotherapy respectively,and the treatment eff ects of the two groups were compared.Results The total eff ective rate and quality of life scores of the combination chemotherapy group were signifi cantly higher than those of the IMRT group(P<0.05),but there was no signifi cant diff erence in the incidence of adverse reactions between the two groups(P>0.05).Conclusion For patients with advanced esophageal cancer,choosing intensity-modulated radiotherapy and concurrent TP chemotherapy for treatment can significantly improve the treatment effi ciency of patients,has high safety,and is also of great signifi cance for improving the quality of life of patients.

关 键 词：食管癌 调强放疗 TP方案化疗 疗效 

分 类 号：R735.1[医药卫生—肿瘤]