西藏地区藏族胃食管反流病患者酸反流与下食管括约肌压力的研究  

Analysis of the LES resting pressure in Tibetan patients with gastroesophageal reflux disease

作　　者：欧珠美朵[1] 尼珍[1] 王中华[1] OU zhu mei duo;NI Zhen;WANG Zhong-hua(Department of Gastroenterology,Tibet Autonomous Region Peoples Hospital,Xizang Lasa 850000,China)

机构地区：[1]西藏自治区人民医院消化内科,西藏拉萨850000

出　　处：《临床医药文献电子杂志》2020年第64期7-7,12,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的了解西藏地区藏族胃食管反流病患者酸反流与下食管括约肌压力之间的关系,探讨下食管括约肌压力在藏族胃食管反流发生中所起的作用。方法对符合GERD诊断标准的50例藏族患者,进行高分辨食管测压检查及24 h食管PH动态监测,根据24 h食管pH监测结果,以Demeester评分<14.72为标准,将50例患者分为生理性酸反流组和病理性酸反流组,比较两组下食管括约肌压力(LESP)。结果病理性酸反流组LESP较生理性酸反流组低,两组差异有统计学意义(P<0.05)。结论西藏地区GERD患者病理性酸反流与LESP密切相关。Objective To investigate the LES resting pressure in Tibetan patients with gastroesophageal reflux disease(GERD),and to provide help for clinical diagnosis and treatment.Methods Fifty GERD patients from Sep.2015 to Dec.2019 in Tibet Autonomous Region Peoples Hospital were enrolled in the study.These patients were divided into the physiological acid reflux group(Demeester score<14.72)and pathologic acid reflux group(Demeester score≥14.72).The general LES resting pressure of two groups were analyzed.Results The LES resting pressure in the pathologic acid reflux group were significantly lower than those in the physiological acid reflux group(P<0.05).Conclusion Compared with physiological acid reflux patients,The LES resting pressure of the pathologic acid reflux patients with GERD is lowered,and the degree of acid exposure is obvious.

关 键 词：胃食管反流病 高分辨率食管测压 食管反流监测 

分 类 号：R571[医药卫生—消化系统]