表没食子儿茶素没食子酸酯的辐射防护作用及其机制研究进展  

Research progress on the radioprotective effect of epigallocatechin gallate and its mechanism

作　　者：薛琦 王曼 刘丽波[1] XUE Qi;WANG Man;LIU Libo(School of Public Health Jilin University,NHC Key Laboratory of Radiobiology,Changchun 130021,China)

机构地区：[1]吉林大学公共卫生学院国家卫生健康委员会放射生物学重点实验室,长春130021

出　　处：《辐射研究与辐射工艺学报》2020年第5期1-9,共9页Journal of Radiation Research and Radiation Processing

摘　　要：本文采用文献资料分析、总结的方法对表没食子儿茶素没食子酸酯(Epigallocatechin-3-gallate,EGCG)的辐射防护作用及其机制进行了综述。EGCG在造血系统、免疫系统和放射性肺损伤等方面具有辐射防护作用,作用机制与其清除自由基、抗氧化、抗凋亡等作用有关。The radiation protection effect and mechanism of epigallocatechin-3-gallate(EGCG)were reviewed by analyzing and summarizing the literature.EGCG has a radiation protection effect on the hematopoietic system,immune system,and radiation lung injury,and its mechanism of action is related to its scavenging of free radicals,anti-oxidation,anti-apoptosis and other effects.

关 键 词：表没食子儿茶素没食子酸酯 辐射防护 自由基 抗氧化 抗凋亡 DNA损伤 

分 类 号：R818.74[医药卫生—放射医学] R852.7[医药卫生—临床医学]