和肽素水平变化与心脏神经官能症相关性分析  

Correlation analysis between changes in copeptin levels and cardiac neurosis

作　　者：石红梅[1] 曾文轩 王文艳[1] 粟虹[1] 李芳[1] SHI Hongmei;ZENG Wenxuan;WANG Wenyan;SU Hong;LI Fang(Health Care Ward of Affiliated Hospital of Guilin Medical College,Guilin 541001,Guangxi,China)

机构地区：[1]桂林医学院附属医院医疗保健病区,广西桂林541001

出　　处：《中南医学科学杂志》2020年第5期528-530,547,共4页Medical Science Journal of Central South China

基　　金：桂林市科学研究与技术开发计划项目(2016012706-10)。

摘　　要：探讨血清和肽素水平变化与心脏神经官能症的相关性。收集确诊为心脏神经官能症患者60例作为试验组,健康人员60例作为正常对照组。检测并比较两组血清和肽素水平,并分析其相关性。结果显示:心脏神经官能症发作时血清和肽素水平明显高于缓解后水平(P<0.05)。血清和肽素水平与女性和糖尿病等心脏神经官能症危险因素呈正相关,与年龄和高血压等心脏神经官能症危险因素无明显相关性。≥75%分位数的血清和肽素水平能作为心脏神经官能症发病的一个独立检测标志物。结果提示:血清和肽素水平与心脏神经官能症密切相关,可作为心脏神经官能症发病的诊断标志物。To investigate the relationship between changes in serum copeptin levels and cardiac neurosis.Collect 60 patients diagnosed with cardiac neurosis as the experimental group,and 60 healthy persons as the normal controls.Serum copeptin levels were measured and compared,and their correlations were analyzed.The results show that serum copeptin levels were significantly higher in the onset of cardiac neurosis than in post-remission(P<0.05).Serum copeptin levels were positively correlated with women and diabetes,and were not significantly associated with age and hypertension.Serum copeptin levels of≥75%quantiles can serve as an independent marker of the onset of cardiacneurosis.The results suggest that serum and copeptin levels are closely related to cardiac neurosis and can be used as diagnostic markers for the onset of cardiac neurosis.

关 键 词：心脏神经官能症 和肽素 预测指标 发作 缓解 

分 类 号：R749.7[医药卫生—神经病学与精神病学]