Three-year follow-up in advanced pediatric keratoconus:thin corneas may not have pachymetry properly assessed after crosslinking  

作　　者：Rosalia Antunes-Foschini Sidney Júlio Faria-e-Sousa 

机构地区：[1]Hospital das Clínicas,Medical School of Ribeirao Preto,University of Sao Paulo,Ribeirao Preto 14049-900,Brazil [2]Department of Ophthalmology,Otorhinolaryngology,Head and Neck Surgery,Medical School of Ribeirao Preto,University of Sao Paulo,Ribeirao Preto 14049-900,Brazil

出　　处：《International Journal of Ophthalmology(English edition)》2020年第10期1561-1566,共6页国际眼科杂志（英文版）

基　　金：Supported by Fundacao de Apoio ao Ensino,Pesquisa e Assistência-2017。

摘　　要：AIM:To analyze the crosslinking(CXL)effects in pediatric keratoconus,and to identify the patients’corneal characteristics whose pachymetry could not be adequately evaluated by Scheimpflug method after procedure.METHODS:Consecutive pediatric patients with progressive keratoconus underwent CXL were included.Best-corrected visual acuity(BCVA)and spheric equivalent(SE)were measured before and after CXL.After CXL,groups 1 and 2 were divided based on the posterior surface Pentacam quality specifications(QS):"OK"(Group 1)and"not OK"(Group 2).The mean(RmF and RmB)and minimum(RminF and RminB)radius of curvatures of the anterior and posterior corneal surfaces,and the thinnest pachymetry(Pmin)were measured preoperatively at 3,6,12,24,and 36 mo.Haze was annotated.RESULTS:Twenty-six patients(14 men,mean age 14±1.8 y)and median Kmax of 59.9 D initially and 61.4 D preoperatively were treated.BCVA was not different before and 24 mo after CXL.Group 2 statistically differed to group 1 in that SE was more myopic before and with no difference 24 mo after CXL;RmF and RmB were steeper and Pmin was thinner pre-surgically.Group 2,in which pachymetric changes could not be adequately evaluated after surgery,presented with significant RmF flattening,a shift to hyperopia,and more haze after CXL.CONCLUSION:Patients whose pachymetry could not be adequately evaluated after CXL had steeper and thinner corneas before surgery.The predictive factors for impaired QS after CXL are RmF,RmB,and Pmin.In advanced keratoconus,alternative methods to analyze pachymetry and the posterior surface should be considered.

关 键 词：KERATOCONUS cross-linking corneal pachymetry corneal topography corneal opacity 

分 类 号：R772.2[医药卫生—眼科]