多层螺旋CT观察COVID-19患者肾上腺的形态学变化  

Morphological study of adrenal gland in patients with COVID-19 using multi-slice spiral CT

作　　者：李晓燕[1] 吕发金[2] 杨全[1] 周永霞[1] 廖娟[3] 陈瑶 刘筱霜 Li Xiaoyan;Lv Fajin;Yang Quan;Zhou Yongxia;Liao Juan;Chen Yao;Liu Xiaoshuang(Department of Radiology,Yongchuan Hospital of Chongqing Medical University,Yongchuan 402160,China;Department of Radiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China;Department of Central Laboratory,Yongchuan Hospital of Chongqing Medical University,Yongchuan 402160,China;Department of Radiology,Chongqing Three Gorges Central Hospital,Wanzhou 404100,China)

机构地区：[1]重庆医科大学附属永川医院放射科,402160 [2]重庆医科大学附属一院放射科,400010 [3]重庆医科大学附属永川医院中心实验室,402160 [4]重庆三峡中心医院放射科,404100

出　　处：《中华内分泌外科杂志》2020年第5期387-392,共6页Chinese Journal of Endocrine Surgery

基　　金：重庆市永川区自然科学基金项目(Ycstc2020nb0207)。

摘　　要：目的多层螺旋CT观察新型冠状病毒肺炎(COVID-19)患者肾上腺的大小、密度及其动态变化。方法回顾性分析67例COVID-19患者(简称新冠组)和70例正常对照组的肾上腺CT平扫图像。新冠组根据临床分型分为普通型、重型两组。测量对照组(单时相)和新冠组(多时相)的肾上腺厚度和CT值,并计算肾上腺/竖脊肌CT密度比值。结果双侧肾上腺的体部、内外侧支厚度在新冠组入院、出院时与对照组比较差异均有统计学意义(P<0.05),新冠组大于对照组;肾上腺/竖脊肌CT值比差异均无统计学意义。右侧肾上腺内侧支最大厚度作为诊断标准所得的ROC曲线下面积最大(0.881)。新冠组患者双侧肾上腺体部、内外侧支厚度和肾上腺/竖脊肌CT值比在不同时期组间比较差异均无统计学意义。结论COVID-19患者双侧肾上腺轻微肿胀,体部、内外侧支厚度略大于正常肾上腺,密度无异常,在病程中无明显动态变化。Objective To observe the size and density of adrenal gland,and the dynamic changes in patients with COVID-19.Methods Study sample consisted of 67 patients diagnosed as COVID-19(COVID-19 group)and 70 normal controls.COVID-19 group were divided into two groups:ordinary cases and severe cases.The CT value and thickness of adrenal gland in the control group(uni-temporal)and the COVID-19 group(multi-temporal)were measured,the CT value of adreal/erector spinae were calculated.Results Compared with the control group,the COVID-19 group had bigger body,medial and lateral branches of bilateral adrenal gland(P<0.05).There was no significant difference between the CT value of adrenal/erector spinae for the two groups.Receiver operating characteristic curve analysis showed the thickness of right medial adrenal limb in detecting diffuse adrenal hyperplasia was the best(0.881).And there was no significant difference in the CT value of adrenal/erector spinae,thickness of bilateral adrenal body,medial and lateral branches in COVID-19 group at different times.Conclusion The bilateral adrenal glands of COVID-19 patients were slightly swollen,adrenal body,medial and lateral branches were slightly bigger than the normal adrenal glands,but the density was normal,and there were no dynamic changes during the course of the disease.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 计算机断层扫描 肾上腺 

分 类 号：R73[医药卫生—肿瘤] R322.5+6[医药卫生—临床医学]