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作 者:陈勇[1] 杨睿芊 卞冬雪 陈健海 Chen Yong
机构地区:[1]南京中医药大学附属盐城市中医院,江苏盐城224002
出 处:《中医临床研究》2020年第25期97-100,共4页Clinical Journal Of Chinese Medicine
摘 要:目的:观察健脾清幽汤联合四联药物治疗幽门螺杆菌(Helicobacter pylori,Hp)根除失败后慢性胃炎的临床疗效。方法:将所有入选患者随机分成治疗组与对照组,对照组予以胶体果胶铋胶囊与雷贝拉唑钠肠溶片,均餐前口服;克拉霉素缓释片与阿莫西林胶囊,均餐后服用。治疗组同时加用健脾清幽汤。治疗结束后4周后复查14C呼气试验及观察临床症状改善情况。结果:治疗组Hp根除率优于对照组,P<0.01;治疗组对临床症状的改善优于对照组,P<0.01;总体疗效对比治疗组亦优于对照组,0.01<P<0.05。结论:健脾清幽汤联合西药补救治疗Hp感染性慢性胃炎可明显提高幽门螺杆菌根除率并改善临床症状,提高临床治疗效果。Objective:To observe the curative effect of the Jianpi Qingyou decoction(健脾清幽汤)plus quadruple drug on Hp infectious chronic gastritis.Methods:100 cases were randomly divided into the control group and treatment group.The control group received colloidal pectin bismuth capsules and rabeprazole sodium enteric-coated tablets,clarithromycin sustained-release tablets and amoxicillin capsules.The treatment group was treated with the Jianpi Qingyou decoction more.Results:The Hp eradication rate in the treatment group was superior to that in the control group(P<0.01).The clinical symptom improvement in the treatment group was superior to that in the control group(P<0.01).The total effective rate in the treatment group was higher than the control group(0.01<P<0.05).Conclusion:The Jianpi Qingyou decoction plus western medicine can significantly improve the eradication rate of Hp,the clinical symptoms and the efficiency.
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