快速冰冻切片与石蜡切片用于卵巢肿瘤诊断的效果比较  

Comparison of the effect of rapid frozen section and paraffin section in the diagnosis of ovarian tumor

作　　者：王君可 Wang Junke(Department of Pathology,the First Peoples Hospital of Yongkang,Yongkang,Zhejiang 321300,China)

机构地区：[1]浙江省永康市第一人民医院病理科,321300

出　　处：《中国基层医药》2020年第20期2440-2443,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省医学会临床科研基金项目(2017ZYC-A102)。

摘　　要：目的 比较快速冰冻切片与石蜡切片用于病理诊断卵巢肿瘤的效果.方法 选取永康市第一人民医院2017年2月至2018年12月手术切除的卵巢肿瘤组织标本80例,均行快速冰冻切片、石蜡切片病理诊断.比较两种检查方式的检查时间、诊断结果.结果 快速冰冻切片检查时间为(34.48 ±4.16)min,短于石蜡切片病理诊断的(182.63 ±2.12)min,差异有统计学意义(t=283.804,P<0.05);石蜡切片病理诊断良性肿瘤、恶性肿瘤、交界性肿瘤分别为45例、21例、14例,快速冰冻切片诊断分别为44例、19例、13例,完全符合率、延迟诊断率、误诊率分别为95.00%(76/80)、1.25%(1/80)、3.75%(3/80).结论 与石蜡切片病理诊断比较,卵巢肿瘤快速冰冻切片的检查时间短且完全符合率高,但有误诊情况存在,医生应提高操作技能及切片取材和制作质量.Objective To compare the efet of rapid frozen section and paraffin section in the diagnosis of ovarian tumor.Methods From February 2017 to December 2018,80 tissue samples of ovarian tumor were selected from the First Peoples Hospital of Yongkang,all of them were diagnosed by rapid frozen section and paraffin section.The examination time and diagnosis results of the two methods were compared.Results The time of rapid frozen section examination was(34.48±4.16)min,which was shorter than that of paraffin section pathology diagnosis[(182.63±2.12)min],the difference was statistically significant(t=283.804,P<0.05).The pathological diagnosis of benign tumor,malignant tumor and borderline tumor of paraffin section were 45 cases,21 cases and 14 cases,respectively,which of rapid frozen section examination were 44 cases,19 cases and 13 cases,respectively.The perfect match rate,delayed diagnosis rate and misdiagnosis rate were 95.00%(76/80),1.25%(1/80)and 3.75%(3/80),respectively.Conclusion Compared with the pathological diagnosis of parafin section,the rapid frozen section examination of ovarian tumor has shorter time and higher rate of complete coincidence,but has misdiagnosis.Doctors should improve the operation skills and the quality of section materials and production.

关 键 词：卵巢肿瘤 冷冻超薄切片术 石蜡包埋 实验室技术和方法 病理学 临床 延误诊断 细胞诊断学 诊断 

分 类 号：R737.31[医药卫生—肿瘤] R730.43[医药卫生—临床医学]