乳腺导管内癌手术方案选择的相关因素及对患者生存状况的影响研究  

Study on the Factors related to the Selection of surgical Options for intraductal Carcinoma of Breast and its Influence on the Survival of Patients

作　　者：龚子永 GONG Ziyong(Breast Department,Xinxiang First People's Hospital,Xinxiang Henan 453000,China)

机构地区：[1]新乡市第一人民医院乳腺科,河南新乡453000

出　　处：《临床研究》2020年第11期26-27,共2页Clinical Research

摘　　要：目的探讨乳腺导管内癌手术方案选择的相关因素及其对患者生存状况的影响。方法选取2010年1月—2018年12月期间新乡市第一人民医院收治的258例乳腺导管内癌女性患者分为保乳组(n=70)和非保乳组(n=188)。比较两组患者的临床病理资料和医生相关资料。结果保乳组的年龄≤45岁例数,学历为大学及以上文化程度例数、手术切除活检例数,主刀医生每周手术量<10台的比例显著高于非保乳组,差异显著(P<0.05)。多因素logistic回归分析结果表明,年龄≤45岁、手术切除活检是患者行保乳手术的独立影响因素,差异显著(P<0.05)。随访结果表明保乳组、非保乳组患者期间分别发生3例、7例肿瘤事件。结论年龄≤45岁、手术切除活检的患者更容易选择进行保乳手术。Objective To explore the factors related to the selection of surgical options for intraductal carcinoma of breast and its influence on the survival of patients.Methods From January 2010 to December 2018,258 female patients with ductal carcinoma were divided into two groups:breast-conserving group(n=70)and non-breast-conserving group(n=188).The clinicopathologic data and doctor-related data were compared between the two groups.Results The number of cases whose age≤45 in breast-conserving group,the number of examples of college education and above,number of surgical biopsy,proportion of solo surgeons performing less than 10 operations per week was higher than that of non-breast-conserving group(P<0.05).Multivariate logistic regression analysis showed that age≤45 years and surgical excision biopsy were the independent influencing factors of breast-conserving surgery(P<0.05).The follow-up results showed that there were 3 and 7 tumor events in breast-conserving group and non-breast-conserving group.Conclusion Breast-conserving surgery is more likely to be performed in patients younger than 45 years of age who have undergone surgical excision and biopsy.

关 键 词：乳腺导管内癌 保留乳房的乳腺癌改良根治术 乳房切除术 手术方案 

分 类 号：R737.9[医药卫生—肿瘤]