Kimura病临床诊治进展  

Clinical features,pathogenesis,and treatment strategy of Kimura disease

作　　者：张雪晗 焦洋[2] ZHANG Xue-han;JIAO Yang(Department of Health Care,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of General Internal Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院保健医疗部,北京100730 [2]中国医学科学院,北京协和医学院,北京协和医院全科医学科(普通内科),北京100730

出　　处：《中华临床免疫和变态反应杂志》2020年第4期397-400,共4页Chinese Journal of Allergy & Clinical Immunology

摘　　要：Kimura病是一种发病机制尚不明确的慢性炎症性疾病。临床特征性表现包括:常见于头颈部的皮下肿块伴局部淋巴结肿大、血液中嗜酸性粒细胞增多以及血清IgE水平增高。目前对于该疾病的优选治疗方案尚存在争议。本文综述近年Kimura病临床特点、Kimura病与IgG4相关疾病和恶性肿瘤相关关系,以及优选诊疗策略等方面的相关研究进展。Kimuras disease(KD)is a chronic inflammatory disorder of unknown etiology.It typically presents as subcutaneous nodules,predominantly in the head and neck region,regional lymphadenopathy,elevated serum eosinophil counts and serum immunoglobulin E levels.The optimal treatment for KD remains controversial.This review will focus on the update in the clinical features,its relationship with IgG4-related disease,malignant transformation and the optimal treatment strategy in recent years.

关 键 词：KIMURA病 临床特点 IgG4相关疾病 治疗 

分 类 号：R73[医药卫生—肿瘤]