噬菌体展示肽库技术在胃癌研究与治疗中的进展  

PROGRESS OF PHAGE DISPLAY LIBRARY IN THE STUDY AND THERAPY OF GASTRIC CANCER

作　　者：刘芳远 苏秀兰[1] Liu Fang-yuan;Su Xiu-lan(Research Center for Clinical Medicine,The Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010050 China)

机构地区：[1]内蒙古医科大学附属医院临床医学研究中心,内蒙古呼和浩特010050

出　　处：《内蒙古医科大学学报》2020年第5期548-552,共5页Journal of Inner Mongolia Medical University

基　　金：国家自然科学基金项目(81960560)。

摘　　要：胃癌是我国最常见的消化道肿瘤之一。近几年,胃癌早期诊断以及低副作用的有效治疗已经成为研究人员重点关注的方向和领域。噬菌体展示肽库技术(PDL)作为分析蛋白质之间相互作用的有效方法,具有简便、高效、高通量等优点,这使得PDL在胃癌的诊断检测和靶向治疗领域展示出了极大的研究价值和潜力。本文就目前PDL技术在胃癌诊断和治疗领域中的研究进展进行综述。Gastric cancer is one of the most common deadly tumors in China.Researches on gastric cancer mainly focus on early diagnosis and effective treatment with low side effects.Phage display library technology(PDL),as an efficient and convenient tool for studying the interaction mechanism between proteins,has a great prospect in the field of early diagnosis and targeted therapy of gastric cancer.In this review,we will focus on the progress and application of the detection and treatment in gastric cancer.

关 键 词：胃癌 噬菌体展示肽库 靶向治疗 

分 类 号：R573[医药卫生—消化系统]