滴丸剂的剂型研究及临床应用进展  

Progress in dosage form development and clinical applications of dropping pills

作　　者：李爽 谷福根[2] LI Shuang;GU Fugen(School of Pharmacy,Inner Mongolia Medical University,Hohhot,Inner Mongolia,010110 P.R.China;Affiliated Hospital,Inner Mongolia Medical University,Hohhot,Inner Mongolia,010050 P.R.China)

机构地区：[1]内蒙古医科大学药学院,内蒙古呼和浩特010110 [2]内蒙古医科大学附属医院,内蒙古呼和浩特010050

出　　处：《华西药学杂志》2020年第5期579-583,共5页West China Journal of Pharmaceutical Sciences

摘　　要：滴丸具有药物溶出快、起效快、生物利用度高、不良反应小、制备工艺简单以及质量易控等优点。滴丸新剂型研究包括缓释滴丸、乳剂滴丸、结肠靶向滴丸、肠溶滴丸、脉冲控释滴丸等。滴丸广泛应用于治疗心绞痛、慢性充血性心衰、哮喘等疾病。现对中国滴丸剂的剂型研究及临床应用情况进行综述。Dropping pills have many characteristics such as rapid dissolution and onset,high bioavailability,few side effect,simple preparation process and easy quality control.New dosage forms of dropping pills mainly include sustained-release,emulsion type,colon targeting,enteric-dissolutive,pulse controlled-release dropping pills,etc.Furthermore,dropping pills are now widely applied in the prevention and treatment of angina pectoris,chronic congestive heart failure,etc.In order to provide reference,dosage form research and clinical application of dropping pills in China are reviewed.

关 键 词：滴丸 新剂型 溶出 缓释 肠溶 生物利用度 临床应用 

分 类 号：R94[医药卫生—药剂学]