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作 者:陈丽娜[1] 张立军[1] CHEN Li’na;ZHANG Lijun(The Third People’s Hospital of Dalian,Dalian 116023,China;不详)
机构地区:[1]辽宁省大连市第三人民医院,辽宁大连116023
出 处:《中国医学创新》2020年第29期73-77,共5页Medical Innovation of China
摘 要:目的:观察1.8 mm微切口超声乳化吸除术治疗急性闭角型青光眼的临床效果。方法:前瞻性随机对照临床试验研究,选择2018年1月-2019年1月在本院诊治的急性闭角型青光眼患者80例(80眼),随机将其分为A组和B组,各40例(40眼)。A组采用1.8 mm微切口超声乳化吸除术,B组采用传统3.0 mm小切口超声乳化吸除术。末次随访时间为术后3个月,比较两组最佳矫正视力(best corrected visual acuity,BCVA)、眼压、平均超声能量(AVE)、有效超声时间(EPT)、角膜内皮细胞计数、角膜厚度、散光情况。结果:两组术后1 d、1周、1个月、3个月的矫正视力和眼压比较,差异均无统计学意义(P>0.05)。A组的AVE低于B组,EPT短于B组,差异均有统计学意义(P<0.05)。B组术后1周、1个月、3个月的角膜内皮计数均低于A组,差异均有统计学意义(P<0.05)。两组术后1 d、1周角膜厚度均高于术前,且B组均高于A组,差异均有统计学意义(P<0.05);但两组术后1、3个月的角膜厚度比较,差异均无统计学意义(P>0.05)。术后3个月,B组SIA明显高于A组,差异有统计学意义(P<0.05)。结论:1.8 mm微切口超声乳化吸除术治疗急性闭角型青光眼角膜,可减轻内皮损伤轻和手术源性散光,值得临床应用。Objective:To observe the efficiency of 1.8mm microincision phacoemulsification in treatmeng of acute angle-closure glaucoma.Method:A prospective randomized controlled clinical trial was conducted to select 80 patients(80 eyes)with acute angle-closure glaucoma who were treated in our hospital from January 2018 to January 2019.They were randomly divided into group A and group B,40 patients(40 eyes)each.Group A adopted 1.8 mm microincision phacoemulsification and group B adopted traditional 3.0 mm microincision phacoemulsification and phacoemulsification.The last follow-up time was 3 months after the operation,BCVA,IOP,AVE,EPT,count of corneal endothelial cells,corneal thickness,and astigmatism were compared between the two groups.Result:There were no statistically significant differences in corrected visual acuity and IOP between the two groups at 1 d,1 week,1 month,and 3 months after operation(P>0.05).AVE in group A was lower than that in group B,EPT was shorter than that in group B,the differences were statistically significant(P<0.05).The corneal endothelium counts of group B at 1 week,1 month and 3 months after operation were all lower than those of group A,with statistically significant differences(P<0.05).Corneal thickness 1 d and 1 week after operation in both groups were higher than those before operation,and corneal thickness in group B were higher than those in group A,with statistically significant differences(P<0.05).However,there were no statistically significant differences in corneal thickness between the two groups at 1 and 3 months after operation(P>0.05).3 months after the operation,SIA in group B was significantly higher than that in group A,with statistically significant difference(P<0.05).Conclusion:1.8 mm microincision phacoemulsification for acute ange-closure glaucoma can reduce the endothelium injury and surgical astigmatism,which is worthy of clinical application.
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