肺癌患者口服桂芝茯苓丸加减的临床探讨  

Clinical Study on the Modification and Subtraction of Guizhi Fuling Pills for Patients with Lung Cancer

作　　者：杨文刚[1] 张佩文[1] 陈磊[1] 邓永[1] 施进[1] 颜嵩 YANG Wen-gang;ZHANG Pei-wen;CHEN Lei;DENG Yong;SHI Jin;YAN Song(Department of Thoracic Surgery,Sheyang County People's Hospital,Sheyang,Jiangsu Province,224300 China)

机构地区：[1]射阳县人民医院胸外科,江苏射阳224300

出　　处：《世界复合医学》2020年第9期132-134,共3页World Journal of Complex Medicine

摘　　要：目的探讨对肺癌手术患者采取口服桂芝茯苓丸加减以提高治疗效果的临床观察。方法选取该院在2015年1月—2018年6月收治的100例肺癌患者,以数字随机的方法将其分为两组,研究组和对照组,均为50例,对照组采取单纯的肺癌根治术进行治疗,研究组患者先进行桂芝茯苓丸加减口服治疗,疗程结束后再给予患者肺癌根治术进行治疗,对两组临床治疗效果,手术时间,术中出血量,引流管时间及并在等情况进行比较。结果研究组手术时间(115.36±30.63)min,术中出血量(180.68±40.83)mL,淋巴清扫数(14.69±3.88)个,置管引流时间(5.00±2.00)d,术后住院时间(7.00±2.00)d与对照组比较差异无统计学意义(t=1.347、0.584、2.533、1.582、1.099,P>0.05);研究组治疗总体有效率90.00%高于对照组,差异有统计学意义(χ^2=15.689,P<0.05);研究组恶心、呕吐3,头晕头痛3,腹痛腹泻4例,发生率为20.00%(10/50)低于对照组40.00%,差异有统计学意义(χ^2=17.383,P<0.05)。通过对患者进行随访18个月,研究组生存率达到了82.00%(41/50)高于对照组60.00%(30/50),比较差异有统计学意义(χ^2=9.848,P<0.05)。结论肺癌患者口服桂芝茯苓丸加减,可进一步的提高患者手术效果,减少术后化疗期间的不良反应,提高患者生存率。Objective To investigate the clinical observation of taking oral Guizhi Fuling Pills to improve the treatment effect for patients with lung cancer surgery.Methods A total of 100 lung cancer patients admitted to the hospital from January 2015 to June 2018 were selected and divided into two groups by a numerical randomization method.The study group and the control group were both 50 cases.The control group was pure lung cancer radical mastectomy.Patients in the study group were treated with Guizhi Fuling pills plus or minus orally.After the course of treatment,they were treated with radical resection of lung cancer.The clinical treatment effect,operation time,intraoperative blood loss,drainage tube time for the situation were compared.Results The operation time of the study group was(115.36±30.63)min,the intraoperative blood loss was(180.68±40.83)mL,the number of lymphatic dissections(14.69±3.88),the catheterization time was(5.00±2.00)d,and the postoperative hospital stay was(7.00±2.00)d compared with the control group,the difference was statistically significant(t=1.347,0.584,2.533,1.582,1.099,P>0.05);the overall effective rate of treatment in the study group was 90.00%higher than that in the control group,the difference was statistically significant(χ^2=15.689,P<0.05);the study group had nausea,vomiting 3,dizziness and headache 3,abdominal pain and diarrhea in 4 cases,the incidence rate was 20.00%(10/50)lower than that of the control group 40.00%,the difference was statistically significant(χ^2=17.383,P<0.05).By following up the patients for 18 months,the survival rate of the study group was 82.00%(41/50)higher than that of the control group 60.00%(30/50),the difference was statistically significant(χ^2=9.848,P<0.05).Conclusion The oral administration of Guizhi Fuling Pills for lung cancer patients can further improve the surgical effect of patients,reduce adverse reactions during postoperative chemotherapy,and improve the survival rate of patients.It is worthy of clinical promotion.

关 键 词：肺癌 肺癌根治术 口服 桂芝茯苓丸加减 临床探讨 

分 类 号：R734[医药卫生—肿瘤]