乳腺癌术后辅助NP方案化疗的可行性分析  

Feasibility Analysis of Adjuvant NP Chemotherapy after Breast Cancer Surgery

作　　者：张辰铭 Zhang Chenming(Jiamusi Central Hospital,Jiamusi 154002)

机构地区：[1]佳木斯市中心医院,佳木斯154002

出　　处：《数理医药学杂志》2020年第11期1610-1612,共3页Journal of Mathematical Medicine

摘　　要：目的:分析研究乳腺癌术后辅助NP方案(诺维本联合顺铂)化疗的可行性。方法:对乳腺癌术后的79例患者进行回顾性分析研究,随机表原则分为对照组、观察组,对照组34例FEC方案(5-氟尿嘧啶+环磷酰胺+表柔比星),观察组45例实施NP方案,对比分析不同化疗方案实施效果。结果:观察组治疗后近期总有效率、毒副反应与对照组无差异无统计学意义(P>0.05);观察组治疗后的远期无病生存率、总生存率高于对照组,差异显著(P<0.05)。结论:乳腺癌术后实施NP方案化疗,其预后效果与FEC方案基本一致,但针对心功能异常者,NP方案应用效果更为显著。Objective:To analyze and study the feasibility of adjuvant NP chemotherapy(novaben+cisplatin)after breast cancer surgery.Methods:Retrospective analysis was carried out on 79 cases of breast cancer patients after operation.All patients were divided into control group and observation group by random table method.The control group(34 cases)received FEC regimen(5-fluorouracil+cyclophosphamide+epirubicin),while the observation group received(45 cases)received NP regimen,and the effect of different chemotherapy regiments was compared and analyzed.Results:There was no significant difference between the observation group and the control group in short-term total effective rate and toxic and side effects after treatment(P>0.05),and the long-term disease-free survival rate and overall survival rate of the observation group were significantly higher than those of the control group(P<0.05).Conclusion:After breast cancer surgery,the prognostic effect of NP chemotherapy is basically the same as that of FEC chemotherapy,but for patients with abnormal cardiac function,the application effect of NP chemotherapy is more significant.

关 键 词：乳腺癌 NP方案 FEC方案 远期生存率 

分 类 号：R737.9[医药卫生—肿瘤]