肠道微生物与非酒精性脂肪性肝病的研究进展  

Research progress on the relationship between intestinal microorganisms and non-alcoholic fatty liver disease

作　　者：吴杰芳 胥莹[1] 孟淑慧 WU Jiefang;XU Ying;MENG Shuhui(Department of Gastroenterology,The Second affiliated Hospital of Kunming Medical University,Kunming 650101,China)

机构地区：[1]昆明医科大学第二附属医院消化内科,650101

出　　处：《中国老年保健医学》2020年第5期105-107,共3页Chinese Journal of Geriatric Care

摘　　要：非酒精性脂肪性肝病发病率逐年上升,其发病机制复杂,随着研究的深入,发现肠道微生物失衡可以促进非酒精性脂肪性肝病的发生,而通过对肠道微生物的调节,如增加益生菌,可以逆转肝损伤,证明了肠道微生物在非酒精性脂肪性肝病的形成过程中起着重要作用。本文就肠道微生物对非酒精性脂肪性肝病的影响作用做一综述,阐述二者之间的关系,以指导临床诊治及科研工作。The incidence rate of nonalcoholic fatty liver disease is increasing year by year,and its pathogenesis is rather complex.With the deepening of the study,it was found that intestinal microbial imbalance can promote the occurrence of nonalcoholic fatty liver disease,and the regulation of intestinal microorganisms,such as adding probiotics,can reverse liver injury,which proves that intestinal microorganisms play an important role in the formation of nonalcoholic fatty liver disease.In this paper,the effect of intestinal microbiota on nonalcoholic fatty liver disease was reviewed,and the relationship between them was elaborated,so as to guide clinical diagnosis,treatment and scientific research.

关 键 词：非酒精性脂肪性肝病 肠道微生物 益生菌 

分 类 号：R575.5[医药卫生—消化系统]