胸腹腔镜联合食管癌切除术对食管癌患者临床预后的影响  

Effect of thoracoscopy and laparoscopy combined with resection of esophageal carcinoma on clinical prognosis of patients with esophageal cancer

作　　者：杏福宝 张雷[1] 唐震[1] 李小军[1] 贡会源[1] 王彪[1] 朱潇 XING Fubao;ZHANG Lei;TANG Zhen;LI Xiaojun;GONG Huiyuan;WANG Biao;ZHU Xiao(Thoracic Surgery Department,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233000,China)

机构地区：[1]蚌埠医学院第一附属医院胸外科,安徽蚌埠233000

出　　处：《临床医学研究与实践》2020年第31期67-69,共3页Clinical Research and Practice

基　　金：2019年度院一般新技术项目(No.2019118)。

摘　　要：目的探究胸腹腔镜联合食管癌切除术对食管癌患者临床预后的影响。方法回顾性分析2017年1月至2019年12月于我院实施手术治疗的81例食道癌患者的临床资料,根据手术方式将患者分为A组(41例,胸腹腔镜联合食管癌根治术)和B组(40例,传统三切口食管癌根治术)。比较两组术前1 d及术后1、4、7 d的血清白蛋白(ALB)和前白蛋白(PA)水平及住院指标。结果两组患者围手术期均无死亡病例及术后严重并发症的发生。术后4、7 d,A组的血清ALB和PA水平高于B组(P<0.05)。A组的术中失血量少于B组,术后胸引管拔管时间、住院时间均短于B组,手术时间长于B组,住院总费用高于B组(P<0.05)。结论相较于传统开放手术,虽然胸腹腔镜联合食管癌根治术的住院费用多、手术时间长,但其在术中出血量、术后胸引管拔管时间及住院时间方面更优,且有利于术后患者机体营养状态的恢复,值得临床推广。Objective To explore the effect of thoracoscopy and laparoscopy combined with resection of esophageal carcinoma on clinical prognosis of patients with esophageal cancer.Methods The clinical datas of 81 patients with esophageal cancer who underwent surgical treatment in our hospital from January 2017 to December 2019 were retrospectively analyzed.The patients were divided into group A(41 cases,thoracoscopy and laparoscopy combined with resection of esophageal carcinoma)and group B(40 cases,traditional three incisions resection of esophageal carcinoma)according to the surgical method.The serum albumin(ALB)and prealbumin(PA)levels at 1 d before operation and 1,4,7 d after operation and hospitalization indexes were compared between the two groups.Results There were no death cases and serious postoperative complications in both groups.At 4 and 7 d after surgery,the levels of serum ALB and PA in the group A were higher than those in the group B(P<0.05).The intraoperative blood loss volume of the group A was less than that of the group B,postoperative thoracic drainage tube extubation time and hospitalization time of the group A were shorter than those of the group B,the operation time was longer than that of the group B,and the total hospitalization cost was higher than that of the group B(P<0.05).Conclusion Compared with the traditional open surgery,although the cost of hospitalization of thoracoscopy and laparoscopy combined with resection of esophageal carcinoma is more expensive and the operation time is longer,it is better in the intraoperative blood loss volume,postoperative thoracic drainage tube extubation time and hospitalization time,and it is conducive to the recovery of postoperative nutritional status of patients,which is worthy of clinical promotion.

关 键 词：食管癌 胸腹腔镜 食管癌切除术 

分 类 号：R735.1[医药卫生—肿瘤]