多孔银-磁性甲壳素微球的制备及其抗菌性能  

Fabrication and Antibacterial Properties of Porous Sliver-Magnetic Chitin Microspheres

作　　者：江承佳 余宁翔 熊华[1] JIANG Chengjia;YU Ningxiang;XIONG Hua(State Key Laboratory of Food Science and Technology,Nanchang University,Nanchang 330047,China)

机构地区：[1]食品科学与技术国家重点实验室,南昌大学,江西南昌330047

出　　处：《食品与生物技术学报》2020年第9期32-38,共7页Journal of Food Science and Biotechnology

基　　金：国家自然科学基金项目(21667018)。

摘　　要：以甲壳素为原料制备可回收型抗菌材料,研究其抗菌效果,提高甲壳素在食品抑菌保藏等领域的应用。通过溶胶-凝胶、原位合成两步法制备银-磁性甲壳素微球,以大肠杆菌和金黄色葡萄球菌为对象,对其基本特性及抗菌性能进行表征评价。结果表明,材料呈三维多孔纳米纤维状球形,磁珠与纳米银嵌于纤维结构之中,纳米银能够快速、持续释放,对2种试验菌可通过破坏细菌结构完整性实现浓度相关性抗菌效果。New recoverable antibacterial microspheres were fabricated by chitin,and the antibacterial effect of microsphere was studied to extend the application of chitin in fields such as food bacteriostatic preservation.Silver-magnetic chitin microspheres(Ag-Fe3O4-NMs)were prepared by sol-gel and in-situ synthesis methods.The microspheres were characterized and the antibacterial effect was studied on Escherichia coli and Staphylococcus aureus.The results showed that the antibacterial agent was 3D-porous nanofibrous spheres with magnetic beads and AgNP being embedded in the fiber structure.The AgNP in the microspheres could be released quickly and continuously,which showed a concentration-dependent antibacterial activity by destroying the structural integrity of the two test bacteria.

关 键 词：纳米银 磁性 甲壳素微球 抗菌 

分 类 号：TQ314.1[化学工程—高聚物工业]