教研共生发展模式在药化实验教学中的探索  

Exploration on Teaching Mode of Medicinal Chemistry Based on Development Mode of Teaching and Research

作　　者：丁丽娜[1] 高琦冰 高珊珊[1] 郑甲信[1] 李雯[1] 陈卫华[2] DING Li-na;GAO Qi-bing;GAO Shan-shan;ZHENG Jia-xin;LI Wen;CHEN Wei-hua(College of Pharmacy,Zhengzhou University,Henan Zhengzhou 450001;College of Chemistry,Zhengzhou University,Henan Zhengzhou 450001,China)

机构地区：[1]郑州大学药学院,河南郑州450001 [2]郑州大学化学学院,河南郑州450001

出　　处：《广州化工》2020年第21期155-157,共3页GuangZhou Chemical Industry

基　　金：国家自然科学基金青年项目(No.21403200、2019ZZUKCSZ023);郑州大学2020年度校级一流本科课程立项项目(校教务[2020]11号)。

摘　　要：药物化学实验课程作为理论与实践相结合的良好平台,一般由验证性实验(经典药物的指定路线合成)组成。结合药物化学实验中已知药物合成路线的多样性等特点以及现有模式下教学中存在的问题,我们将药物化学实验课程更新为双层次设计课程,即验证性实验和开放性实验(经典药物的开放性路线探索)相结合模式,借此激发学生的研究性思维,实现教学与研究的共生发展模式,培养适应未来发展的创新型人才。As a good platform for the combination of theory and practice,the course of Pharmaceutical Chemistry Experiment is generally composed of confirmatory experiments,which refers to the synthesis of classical drugs.Combined with the characteristics of the diversity of known drug synthesis routes in Pharmaceutical Chemistry Experiment and the problems existing in the teaching under the existing mode,the course of Pharmaceutical Chemistry Experiment was updated into a two-level design course as a combination of confirmatory experiments and open experiments,open experiment referred to the exploration of the open route of classical drugs,in order to stimulate the research thinking of students,realize the symbiotic development model of teaching and research,and train innovative talents to adapt to the future development.

关 键 词：药物化学实验 研究性思维 教学改革 

分 类 号：R914.5[医药卫生—药物化学]