昆明市中老年人幽门螺旋杆菌感染状况及其影响因素  

Analysis of Conditions and Influencing Factors for Helicobacter Pylori Infection in Middle and Old Aged People in Kunming

作　　者：方红丽 田衍[2] 邓苙[1] FANG Hong-li;TIAN Ye;DENG Li(Dept.of Health Management Center,The First Affiliated Hospital of Kumming Medical University,Kunming Yunnan 650032,China;Dept.of Gastrointestinal Surgery,The First Affiliated Hospital of Kumming Medical University,Kunming Yunnan 650032,China)

机构地区：[1]昆明医科大学第一附属医院健康管理中心,云南昆明650032 [2]昆明医科大学第一附属医院胃肠外科,云南昆明650032

出　　处：《昆明医科大学学报》2020年第10期114-118,共5页Journal of Kunming Medical University

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目[2018FE001(-035)]。

摘　　要：目的采用横断面研究昆明地区中老年人幽门螺旋杆菌(Hp)感染状况,分析其影响因素,为中老年人群预防幽门螺旋杆菌感染提供依据。方法回顾性随机抽取2018年12月至2019年12月在昆明地区某三甲医院健康管理中心健康体检的40~79岁体检人群560例作为研究对象,所纳入的研究对象都进行14C-尿素呼气试验检测Hp感染状况,同时采用问卷调查的形式采集体检者一般资料、生活习惯和疾病史等,用统计分析软件SPSS17.0分析Hp感染状况及其影响因素。结果中老年人群幽门螺旋杆菌阳性人数234人,总体感染阳性率41.80%。Logistic回归分析显示饮酒(OR=11.684, 95%CI=6.912~19.750)、家族胃癌史(OR=10.653, 95%CI=6.198~18.309)、慢性胃炎(OR=1.782,95%CI=1.193~2.660)、嗜辣(OR=2.891,95%CI=1.589~5.259)为幽门螺旋杆菌感染的危险因素(P<0.05)。结论昆明地区中老年人的Hp感染阳性率较高,其与嗜辣、饮酒、家族胃癌史、慢性胃炎多种因素相关;应加强健康宣教力度,培养良好生活习惯,做好防控管理工作,是减少人群Hp感染率的重要措施。Objective To explore the influencing factors of Helicobacter pylori infection in Kunming area with a restropective investingation so as to provide the evidence for preventing Helicobacter pylori infection.Methods 560 middle-aged and elderly people on whom the 14 C-urea breath test was performed to detect Hp infection were randomly selected from December 2018 to December 2019 at the Health Management Center of the First Affiliated Hospital of Kunming Medical University. At the same time, questionaire survery was used to collect the general data, medical history, living habits. The data were analyzed by SPSS 17.0 to make sure which were the important Hp infection factors. Results The number of Helicobacter pylori positive in our group was 234, where infection rate was 41.80%. Logistic regression analysis showed that spicy(OR=2.891,95%CI=1.589~5.259), drinking(OR=11.684,95%CI=6.912~19.750), family history of stomach cancer(OR=10.653,95%CI=6.198~18.309), and chronic gastritis(OR=1.782,95%CI=1.193~2.660) were the risk factors for Helicobacter pylori infection. Conclusion The positive rate of Hp infection is high in Kunming,and Hp infection is correlated with various factors. It is necessary to strengthen the health education of Hp. In conclusion, middle-aged and elderly people should cultivate good habits and take good control to prevent Hp infection.

关 键 词：幽门螺旋杆菌 昆明地区 中老年人 影响因素 

分 类 号：R573.3[医药卫生—消化系统] R183.5[医药卫生—内科学]