Prognostic value of admission hyperglycemia on outcomes of thrombolysis in ischemic stroke patients with or without diabetes  

作　　者：Hong-Juan Fang Yue-Song Pan Yong-Jun Wang Chun-Xue Wang Yi-Long Wang Li-Yong Zhong 

机构地区：[1]Department of Endocrinology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China [2]Department of Neurology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China [3]China National Clinical Research Center for Neurological Diseases,Beijing 100070,China [4]Center of Stroke,Beijing Institute for Brain Disorders,Beijing 100070,China [5]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease,Beijing 100070,China

出　　处：《Chinese Medical Journal》2020年第18期2244-2246,共3页中华医学杂志（英文版）

基　　金：supported by grants from the Ministry of Science and Technology of the People’s Republic of China(No.2015BAI12B04);the National Natural Science Foundation of China(No.31672375);Beijing Municipal Science and Technology Commission(D151100002015001);Beijing Natural Science Foundation(7182049);Basic-Clinical Research Cooperation Funding of Capital Medical University(17JL34);Beijing Municipal Administration of Hospitals’Youth Programme(QML20160501)。

摘　　要：Thrombolytic therapy within 4.5 h from symptom onset is a recognized effective and standard therapy for acute ischemic stroke(AIS),but some patients still have a poor clinical outcome.The evaluation and control of predictors for AIS poor clinical outcomes is integral to achieving optimal treatments,but the prognostic value of admission blood glucose(ABG)for this purpose is unclear and still under debate.ABG evaluated in patients without diabetes mellitus(DM)often suggests acute stress hyperglycemia,while ABG may have a close relationship with long-term blood glucose control in patients with DM.However,in most studies about the influence of ABG on the prognosis of recombinant tissue-type plasminogen activator(rtPA)therapy after AIS,patients were not classified into those with and without DM.The present study was designed to investigate the prognostic value of ABG for clinical outcomes of AIS after thrombolysis according to DM status in a Chinese population.

关 键 词：patients acute THROMBOLYSIS 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R587.1[医药卫生—临床医学]