宫颈电灼术治疗HPV持续感染的效果分析  

Effectiveness of cervical electrocautery in the treatment of persistent HPV infection

作　　者：张兴微 Zhang Xingwei(Department of Gynecology and Obstetrics Section 2,Panjin Central Hospital,Panjin,Liaoning,124000,China)

机构地区：[1]盘锦市中心医院妇产科二病区,辽宁盘锦124000

出　　处：《当代医学》2020年第32期96-98,共3页Contemporary Medicine

摘　　要：目的探讨宫颈电灼术治疗人乳头状瘤病毒(human papillomavirus,HPV)持续感染的临床效果。方法选取本院妇科2017年1月至2019年1月收治的80例HPV持续感染患者作为研究对象,按照随机数字表法分为观察组与对照组,各40例。对照组给予保妇康栓治疗,观察组在保妇康栓治疗基础上实施宫颈电灼术,比较两组临床疗效、HPV-DNA转阴率、血清炎症因子水平、生活质量评分、复发率。结果观察组临床总有效率、HPV-DNA转阴率分别为95.00%、85.00%,均高于对照组(P<0.05)。治疗后,观察组CRP、IL-6水平均低于对照组,WHOQOLBREF评分高于对照组(P<0.05)。随访3个月,观察组复发率低于对照组(P<0.05)。结论宫颈电灼术可提高HPV持续感染患者的疗效和HPV-DNA转阴率,可减轻宫颈炎症反应,有利于提升生活质量,减少复发。Objective To investigate the clinical effect of cervical electrocautery in the treatment of persistent human papillomavirus(HPV)infection.Methods 80 patients with persistent HPV infection who admitted to gynecology department of our hospital from January 2017 to January 2019 were selected as study subjects.They were divided into control group and observation group according to the random number table method,with 40 cases in each group.The control group was treated with Baofukang Suppository,the observation group was treated with cervical electrocautery on the basis of Baofukang Suppository.The clinical efficacy,HPV-DNA negative conversion rate,serum inflammatory factor level,quality of life score and recurrence rate were compared between the two groups.Results The total clinical effective rate and HPV-DNA negative conversion rate in the observation group were 95.00%and 85.00%respectively,which were higher than those in the control group(P<0.05).After treatment,the CRP and IL-6 levels in the observation group were lower than those in the control group,and the WHOQOL-BREF scores in the observation group was higher than those in the control group(P<0.05).Followed up for 3 months,the recurrence rate in the observation group was lower than that in the control group(P<0.05).Conclusion Cervical electrocautery can improve the efficacy and negative rate of HPV-DNA in patients with persistent HPV infection,alleviate cervical inflammation,and improve the quality of life,reduce recurrence.

关 键 词：人乳头状瘤病毒持续感染 妇科 保妇康栓 宫颈电灼术 

分 类 号：R737.33[医药卫生—肿瘤]